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Recruiting NCT05732714

NCT05732714 Long Term Cardiovascular Disease Event Risk for Patients Undergoing Major Non-Cardiac Surgery

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Clinical Trial Summary
NCT ID NCT05732714
Status Recruiting
Phase
Sponsor University Health Network, Toronto
Condition Cardiovascular Diseases
Study Type OBSERVATIONAL
Enrollment 50 participants
Start Date 2024-08
Primary Completion 2025-04

Eligibility & Interventions

Sex All sexes
Min Age 45 Years
Max Age 75 Years
Study Type OBSERVATIONAL
Interventions
Healthy lifestyle behaviors around the time of surgery

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 50 participants in total. It began in 2024-08 with a primary completion date of 2025-04.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this observational study is to learn whether the healthy lifestyle choices made around surgery can influence an individual's long term risk of developing cardiovascular disease. Patients will be observed 1-month prior to and 3-months following surgery to assess their risk of developing cardiovascular disease.

Eligibility Criteria

Inclusion Criteria: * Age 45 - 75 years * Scheduled for intermediate- to high risk non-cardiac surgery (intra-thoracic or intra-abdominal surgery, all vascular surgery, intra-cranial neurosurgery, spine surgery) * Expected post-operative length of stay of at least two days, according to the surgeon's expectation * At least two of the following CVD risk factors: History of: Hypertension, Diabetes, Coronary artery disease, Chronic heart failure, Chronic kidney disease, Cerebrovascular disease, Peripheral vascular disease. Obesity (BMI \>25 kg/m2), Current smoking, Poor exercise capacity (\<4 METS) Exclusion Criteria: * Currently participating in a CVD risk reduction program * Patient is scheduled to undergo transplant or has undergone emergency surgery * Life expectancy \<1 year (palliative surgery) * Recent (\<6 months) myocardial infarction or stroke * Surgery scheduled \<1 month * Inability to effectively communicate

Contact & Investigator

Central Contact

Wilton van Klei, MD

✉ Wilton.VanKlei@uhn.ca

📞 416-340-5164

Principal Investigator

Wilton van Klei, MD

PRINCIPAL INVESTIGATOR

University Health Network, Toronto

Frequently Asked Questions

Who can join the NCT05732714 clinical trial?

This trial is open to participants of all sexes, aged 45 Years or older, up to 75 Years, studying Cardiovascular Diseases. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05732714 currently recruiting?

Yes, NCT05732714 is actively recruiting participants. Contact the research team at Wilton.VanKlei@uhn.ca for enrollment information.

Where is the NCT05732714 trial being conducted?

This trial is being conducted at Toronto, Canada.

Who is sponsoring the NCT05732714 clinical trial?

NCT05732714 is sponsored by University Health Network, Toronto. The principal investigator is Wilton van Klei, MD at University Health Network, Toronto. The trial plans to enroll 50 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology