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Recruiting NCT07224789

NCT07224789 Liquid Biopsy for Early Detection of Colorectal Cancer Using Circular RNA

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Clinical Trial Summary
NCT ID NCT07224789
Status Recruiting
Phase
Sponsor City of Hope Medical Center
Condition Colorectal Cancer
Study Type OBSERVATIONAL
Enrollment 600 participants
Start Date 2025-01-15
Primary Completion 2028-06-18

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
cf-circRNA assay

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 600 participants in total. It began in 2025-01-15 with a primary completion date of 2028-06-18.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. This study aims to develop a non-invasive liquid biopsy assay using plasma-derived cell-free circular RNAs (cf-circRNAs) for early and accurate detection of colorectal cancer.

Eligibility Criteria

Inclusion Criteria: * Adults (≥18 years old) * Histologically confirmed colorectal cancer (Stage I-III) * Availability of pre-treatment plasma samples * Written informed consent provided Exclusion Criteria: * History of other active malignancies within the past 5 years * Poor sample quality or hemolysis * Inability to provide informed consent

Contact & Investigator

Central Contact

Goel Ajay, PhD

✉ ajgoel@coh.org

📞 626-218-3452

Principal Investigator

Ajay Goel, PhD

PRINCIPAL INVESTIGATOR

City of Hope Medical Center

Frequently Asked Questions

Who can join the NCT07224789 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Colorectal Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07224789 currently recruiting?

Yes, NCT07224789 is actively recruiting participants. Contact the research team at ajgoel@coh.org for enrollment information.

Where is the NCT07224789 trial being conducted?

This trial is being conducted at Duarte, United States.

Who is sponsoring the NCT07224789 clinical trial?

NCT07224789 is sponsored by City of Hope Medical Center. The principal investigator is Ajay Goel, PhD at City of Hope Medical Center. The trial plans to enroll 600 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology