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City of Hope Medical Center

Total Trials
24
Recruiting
24
Phases
Phase 1, Phase 2

City of Hope Medical Center is a clinical research sponsor with 24 registered studies on ClinicalTrials.gov, of which 24 are actively recruiting participants. Research covers conditions including Advanced Clear Cell Renal Cell Carcinoma, Advanced Sarcomatoid Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma, Metastatic Sarcomatoid Renal Cell Carcinoma.

The trial portfolio spans Phase 1, Phase 2 studies, reflecting a pipeline that may include early-stage safety evaluations, mid-stage efficacy assessments, and large-scale confirmatory trials. All studies listed here are sourced directly from ClinicalTrials.gov and updated daily.

Frequently Asked Questions — City of Hope Medical Center

How many clinical trials has City of Hope Medical Center sponsored?
ClinicalMetric currently tracks 24 clinical trials sponsored by City of Hope Medical Center, of which 24 are actively recruiting participants. These trials cover conditions including Advanced Clear Cell Renal Cell Carcinoma, Advanced Sarcomatoid Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma. Trial counts are updated daily from ClinicalTrials.gov and reflect currently registered studies.
What therapeutic areas does City of Hope Medical Center research focus on?
City of Hope Medical Center clinical trials span Advanced Clear Cell Renal Cell Carcinoma, Advanced Sarcomatoid Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma, Metastatic Sarcomatoid Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8, and additional conditions. The research pipeline includes Phase 1, Phase 2 trials, reflecting work from early-stage safety evaluation through large-scale efficacy studies.
How do I participate in a City of Hope Medical Center clinical trial?
To participate in a City of Hope Medical Center trial, review the active studies listed on this page, check each trial's specific eligibility criteria on ClinicalTrials.gov, and contact the trial site directly—not the sponsor's headquarters. Trial sites are academic medical centers, hospitals, or specialized research clinics. Your physician can facilitate a referral. ClinicalMetric lists all City of Hope Medical Center trials with current recruitment status updated daily.

Clinical Trials by City of Hope Medical Center

NCT07128680 Phase 1
Recruiting

Immunotherapy (Nivolumab and Ipilimumab) With and Without a Live Biotherapeutic Product (EXL01) for the Treatment of Metastatic Renal Cell Cancer

Advanced Clear Cell Renal Cell Carcinoma
NCT06954831 Phase 2
Recruiting

Ultra-hypofractionated Whole Breast Irradiation With Lumpectomy Cavity Boost for the Treatment of Stage I-III Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8
NCT06342440
Recruiting

Early Detection of Advanced Adenomas and Colorectal Cancer

Colorectal Cancer
NCT05757310 Phase 1
Recruiting

A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent Severe Aplastic Anemia

Recurrent Severe Aplastic Anemia
NCT06543381 Phase 1
Recruiting

Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant

Acute Myeloid Leukemia
NCT05225363 Phase 1
Recruiting

Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian Cancer

Platinum-Resistant Ovarian Carcinoma
NCT06130826 Phase 1
Recruiting

Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer

Breast Carcinoma
NCT07224750
Recruiting

A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer

Hepatocellular Carcinoma (HCC)
NCT07741968
Recruiting

A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8
NCT07226154
Recruiting

Prediction of Neoadjuvant Chemotherapy Response in Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma
NCT05751434 Phase 2
Recruiting

A Study on the Effects of Exercise Therapy on Signs of Prostate Cancer

Prostate Cancer
NCT07040982 Phase 1
Recruiting

Asciminib as Maintenance Treatment After Cellular Therapies for Adults With Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
NCT07224841
Recruiting

Development of a cfDNA 5mC/5hmC-based Biomarker Panel to Predict Targeted Therapy Efficacy in mCRC

CRC (Colorectal Cancer)
NCT06675123 Phase 1
Recruiting

Pacritinib in Combination With a BTK Inhibitor for the Treatment of Patients With Relapsed or Refractory Mantle Cell Lymphoma

Recurrent Mantle Cell Lymphoma
NCT06834126 Phase 1
Recruiting

Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial

Locally Advanced Rectal Adenocarcinoma
NCT05805371 Phase 1
Recruiting

PSCA-Targeting CAR-T Cells Plus or Minus Radiation for the Treatment of Patients With PSCA+ Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma
NCT06735664 Phase 1
Recruiting

Zanubrutinib in Combination With Odronextamab for the Treatment of Patients With Richter's Transformation

Recurrent Transformed Chronic Lymphocytic Leukemia
NCT06342414
Recruiting

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

Hepatocellular Carcinoma
NCT06128070 Phase 2
Recruiting

Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome

Acute Lymphoblastic Leukemia
NCT06731894 Phase 2
Recruiting

Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors

Breast Carcinoma
NCT07587229
Recruiting

Alternative Splicing Based Prediction of Chemotherapy Response in Gastric Cancer

Gastric Cancer
NCT07210086 Phase 2
Recruiting

Phase II Non-Randomized Study Evaluating POSLUMA-PSMA PET Response After Oligo- Metastatic/Progressive-directed Treatment With Radiotherapy (PROMPT-R)

Prostate Cancer
NCT07265271
Recruiting

Project for Multi-Omics-Based Early Detection of Hepatocellular Carcinoma (PROMETHEA Study)

Hepatocellular Carcinoma (HCC)
NCT04930653 Phase 2
Recruiting

Extracorporeal Photopheresis and Mogamulizumab for the Treatment of Erythrodermic Cutaneous T Cell Lymphoma

Folliculotropic Mycosis Fungoides
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology