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Recruiting NCT04390425

Limb Occlusion Pressure Tourniquets to Decrease Pain After Surgery

Trial Parameters

Condition Limb Occlusion Pressure
Sponsor The Methodist Hospital Research Institute
Study Type INTERVENTIONAL
Phase N/A
Enrollment 400
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2018-04-06
Completion 2025-12
Interventions
Experimental - Limb Occlusion pressure

Brief Summary

Currently a standard tourniquet pressure is used for orthopedic surgeries. High tourniquet pressure had been associated with adverse side effects such as ischemia, muscle weakness, and post operative pain. Limb Occlusion Pressure, LOP, is based off the patient's systolic blood pressure plus a safety margin and is typically much lower than standard tourniquet pressure. The aim of this study is to determine if using LOP during orthopedic surgeries decreases post-operative pain and opioid consumption and improves patient's outcomes.

Eligibility Criteria

Inclusion Criteria: * The research team will test the central hypothesis that LOP tourniquets will decrease pain and opioid use and improve patients outcomes on healthy adults (above the age of 18) undergoing either open carpal tunnel release, open reduction internal fixation distal radius fracture, cubital tunnel release, trigger finger release, thumb CMC arthroplasty, anterior cruciate ligament reconstruction, or total knee replacements Exclusion Criteria: 1. Prescription pain medications for chronic conditions (\> 6 weeks) 2. Patients who cannot use a tourniquet:( ex. Certain patients with fistulas or PVD, certain patient with Peripheral Vascular Disease) 3. Prior trauma or surgery to the observed limb. 4. Hypotension or hypertension that prevents accurate distal photoplenthysmography probe reading.

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