Lifetime Endurance Exercise to Prevent Coronary Artery Disease
Trial Parameters
Brief Summary
The primary objective of the Master@Heart Trial is to investigate whether lifelong endurance exercise reduces the incidence of non-calcified plaques (both mixed and soft plaques) as compared to late-onset endurance exercise and a non-athletic lifestyle.
Eligibility Criteria
Inclusion Criteria: * Lifelong endurance athletes: * Initiation of endurance sports before the age of 30 years * Activities at regional, national or international level * Sports: triathlon, cycling, distance running (1500 metres and longer) and rowing * Aged 45-70 years * Involved in competition and high-level training: * more than 10 hours per week for cyclists and triathletes * more than 6 hours per week for runners and rowers. * Late-onset endurance athletes: * Initiation of endurance sports after the age of 30 years and at least 6 months ago * Activities at regional, national or international level * Sports: triathlon, cycling, distance running (1500 metres and longer) and rowing * Aged 45-70 years * Involved in competition and high-level training: * more than 10 hours per week for cyclists and triathletes * more than 6 hours per week for runners and rowers. * Healthy non-athletes * subjects seen in the outpatient clinic for a work-related medical check-up * university alumni * sub