| NCT ID | NCT06219694 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Taichung Veterans General Hospital |
| Condition | Chronic Migraine |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2022-01-01 |
| Primary Completion | 2022-05-04 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2022-01-01 with a primary completion date of 2022-05-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
A single-blind randomized controlled trial was conducted from October 2024 to May 2025. Chronic migraine patients were randomly assigned in a 1:1 ratio to receive either Laser acupuncture or sham treatment. The co-primary outcomes were changes in monthly migraine days (MMD) and acute headache medications usage days per month from baseline, and Hospital Anxiety and Depression Scale (HADS), and Beck's Depression Inventory(BDI) evaluation. Evaluations were taken at baseline and each follow-up point. After \>6 months follow up as washing out time, the sham group received complementary laser acupuncture treatment and follow up for another 3 months, compared the Headache related parameters (onset, duration, pain scale, current medication for headache, menstrual cycle).
Eligibility Criteria
Inclusion Criteria: * patients aged above 20 years old and had CM managed pharmacologically, including preventive and/or acute migraine medications, and in addition, those who had refused preventive agent despite recommendation of the neurologist; * patients who had unsatisfactory effect of current pharmacological treatments, defined as they self-reported * patients who had a minimum of one-year history of migraine with or without aura. Exclusion Criteria: * patients who had received another LA therapy or traditional acupuncture at baseline * migraine onset after the age of 50 * cognitive or psychological impairment interfering with the participant's ability to receive LA protocol and describe symptoms * patients with missing data at baseline or during the follow-up period.
Contact & Investigator
Yuan-Chen Liu, M.D
STUDY DIRECTOR
Taichung Veterans General Hospital
Frequently Asked Questions
Who can join the NCT06219694 clinical trial?
This trial is open to participants of all sexes, aged 20 Years or older, studying Chronic Migraine. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06219694 currently recruiting?
Yes, NCT06219694 is actively recruiting participants. Contact the research team at sam7227632@gmail.com for enrollment information.
Where is the NCT06219694 trial being conducted?
This trial is being conducted at Taichung, Taiwan.
Who is sponsoring the NCT06219694 clinical trial?
NCT06219694 is sponsored by Taichung Veterans General Hospital. The principal investigator is Yuan-Chen Liu, M.D at Taichung Veterans General Hospital. The trial plans to enroll 60 participants.
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