NCT07347431 Large Language Model for Understanding and Monitoring Elderly Neurocognition
| NCT ID | NCT07347431 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Northumbria Healthcare NHS Foundation Trust |
| Condition | Dementia |
| Study Type | OBSERVATIONAL |
| Enrollment | 60 participants |
| Start Date | 2026-03-19 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 60 participants in total. It began in 2026-03-19 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Dementia affects millions of people worldwide, and early diagnosis is essential for getting the right care and support. Doctors rely on collateral histories (accounts from family members or caregivers) to understand changes in a person's memory and thinking. However, these histories can be incomplete, unstructured, or difficult to obtain, making diagnosis more challenging. This study will test LUMEN (Large Language Model for Understanding and Monitoring Elderly Neurocognition), an AI-powered conversation tool designed to help caregivers describe their loved one's symptoms more effectively. By asking structured questions and guiding the conversation, LUMEN can create clear, well-organised reports for memory clinic doctors. This could make assessments quicker, more accurate, and less stressful for families. We will test LUMEN in real-world clinics by asking caregivers and doctors to use it and provide feedback. We want to understand how easy it is to use, whether it could improve the quality of information shared, and how it fits into existing NHS memory clinic processes. We will also run co-production workshops with community groups to ensure the tool is accessible to people from diverse cultural and language backgrounds. This research is exciting because it explores how artificial intelligence can improve dementia care. If successful, LUMEN could enhance the diagnostic process, reduce carer burden, and help more people access dementia support sooner. In the future, this tool could be used nationwide in memory clinics, improving care for thousands of families.
Eligibility Criteria
Carers of patients attending Memory Clinic appointments; Aged 18 or over; Both patients and cares can provide informed consent; Basic English literacy Clinicians must have at least 2 years of specialist dementia care experience and be personally responsible for dementia diagnosis; Must be provide informed consent
Contact & Investigator
Judith R Harrison, MBChB PhD
PRINCIPAL INVESTIGATOR
Northumbria Healthcare NHS Foundation Trust
Frequently Asked Questions
Who can join the NCT07347431 clinical trial?
This trial is open to participants of all sexes, aged 65 Years or older, studying Dementia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07347431 currently recruiting?
Yes, NCT07347431 is actively recruiting participants. Contact the research team at Judith.Harrison@newcastle.ac.uk for enrollment information.
Where is the NCT07347431 trial being conducted?
This trial is being conducted at North Shields, United Kingdom.
Who is sponsoring the NCT07347431 clinical trial?
NCT07347431 is sponsored by Northumbria Healthcare NHS Foundation Trust. The principal investigator is Judith R Harrison, MBChB PhD at Northumbria Healthcare NHS Foundation Trust. The trial plans to enroll 60 participants.