NCT06478303 LAnguage-Motor Imagery Circuits to Improve Motor Learning and Language Comprehension
| NCT ID | NCT06478303 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital, Grenoble |
| Condition | Corticospinal Excitability |
| Study Type | OBSERVATIONAL |
| Enrollment | 105 participants |
| Start Date | 2024-07-27 |
| Primary Completion | 2027-07-26 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 105 participants in total. It began in 2024-07-27 with a primary completion date of 2027-07-26.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Recent evidence suggests that cognitive systems do not operate in isolation but interact within broader networks, thus opening new avenues for fundamental and clinical research. An illustrative example is the interaction between language comprehension and motor representations. For instance, motor training (e.g., sports, origami training) can facilitate action verb recognition, whereas motor deficits (e.g., upper limb immobilization) can hinder the processing of action language. Similarly, action language has been shown to affect motor performance. These effects are attributed to an implicit form of motor imagery, an automatic simulation of motor experience (without actual movement) evoked by action words. Interestingly, literature supports the idea that the motor simulations used for imagining an action are also engaged during the reading of action language, leading to similar neurophysiological and behavioral changes in both processes. However, questions remain about the similarity of the simulations generated by motor imagery and action language. This project, encompassing three experimental sequences, aims to address these questions to achieve significant scientific advancements in both theoretical and applied domains.
Eligibility Criteria
Inclusion Criteria: * persons who have given written consent, * healthy subjects * subjects reading and understanding French * right-handed, * affiliated with a social security system, * between 18 and 40 years old, * had completed the TMS inclusion questionnaire or had undergone a medical examination prior to participation in the MRI study. Exclusion Criteria: * Existence of a severe general medical condition: cardiac, respiratory, hematological, renal, hepatic, cancerous, * Regular use of anxiolytics, sedatives, antidepressants, neuroleptics, * Characterized psychiatric pathology, * Ingestion of alcohol prior to the examination, * Persons covered by articles L1121-5 to L1121-8 of the CSP, * Presence of contraindications to MRI or TMS.
Contact & Investigator
Laurent VERCUEIL
PRINCIPAL INVESTIGATOR
CHU Grenoble Alpes
Frequently Asked Questions
Who can join the NCT06478303 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 40 Years, studying Corticospinal Excitability. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06478303 currently recruiting?
Yes, NCT06478303 is actively recruiting participants. Contact the research team at LVercueil@chu-grenoble.fr for enrollment information.
Where is the NCT06478303 trial being conducted?
This trial is being conducted at Grenoble, France, Dijon, France.
Who is sponsoring the NCT06478303 clinical trial?
NCT06478303 is sponsored by University Hospital, Grenoble. The principal investigator is Laurent VERCUEIL at CHU Grenoble Alpes. The trial plans to enroll 105 participants.