Kingston Chronic Obstructive Pulmonary Disease (COPD) Multidimensional Long Term Follow up Cohort
This study follows COPD patients over a long period to better understand their disease and how it progresses. Researchers will track patients with different levels of COPD severity, including those who experience frequent flare-ups, to identify ways to improve their care and quality of life.
Key Objective:The trial aims to identify patterns in COPD progression and factors that lead to worse outcomes, which could help develop better treatment strategies for complex COPD patients.
Who to Consider:People with a diagnosis of COPD who are willing to participate in long-term follow-up visits and assessments should consider enrolling.
Trial Parameters
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Brief Summary
Background: Chronic Obstructive Pulmonary (COPD) patients are the paradigm of the chronic complex patient. Their follow up can sometimes be difficult and challenging (1). There are patients with recurrent exacerbations that put an enormous burden on health care resources (2). They also have multiple comorbidities (3) that can sometimes make their management difficult. In an attempt to coordinate all these efforts KGH, HDH and Providence Care have numerous essential resources to take care of COPD patients like the nurse navigators, nurse practitioners and the pulmonary rehabilitation program. These programs provide an excellent support to the clinical activity of Respirologists and other health care providers. Rationale: The main rationale for the development of the Kingston COPD cohort is to translate that highly demanding clinical activity in a teaching and research oriented activity that could be used by clinicians, medical students, residents and fellows. Having a guideline complained established protocol in COPD patients that are usually follow at KGH and HDH could help in not only in unified the way COPD patients are seeing (preserving the importance of the personalized approach) but most importantly established a multidimensional (clinical, physiological, radiological, laboratory) database. This could help know not only the results of our clinical activity but also have a long term (\>5yrs) database for clinical research projects in collaboration with national and international research groups. Therefore this proposal is important because it will help translate our busy daily clinical work in a highly productive teaching and research activity.
Eligibility Criteria
Inclusion Criteria: 1. Patients ages between 40-85 years old. 2. Smoking history of at least 10 pack year history 3. Active of former smokers 4. Diagnosis of COPD according to the GOLD definition (4): post bronchodilator spirometry FEV1/FVC ≤0.70, including those with other associated respiratory diseases like asthma, bronchiectasis, stable lung cancer or Interstitial Lung Disease. 5. Ability to perform all study procedures (complete pulmonary function tests, six minute walking test (6MWT) and chest computed tomography) and provide/sign informed consent. Exclusion Criteria: 1. Patients not willing to sign the consent form 2. Patients with a life expectancy of less than 3 yrs. 3. Patients in palliative care. 4. Patients with chronic airway obstruction ie: FEV1/FVC≤0.70 of other etiology and without a smoking history of less than 10 packs year history. 5. Patients unable ort not able to perform the pulmonary function test, the 6MWT or the chest CT.