NCT04149496 IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer
| NCT ID | NCT04149496 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Bruce Rose, MD |
| Condition | Polycystic Ovary Syndrome |
| Study Type | INTERVENTIONAL |
| Enrollment | 300 participants |
| Start Date | 2019-05-10 |
| Primary Completion | 2023-04-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 300 participants in total. It began in 2019-05-10 with a primary completion date of 2023-04-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
A protocol was developed to improve pregnancy results after IVM compared to results from studies in the literature. Differences from most published protocols include the use of the Steiner-Tan needle to optimize oocyte environment during oocyte retrieval, use of oral medications and very low doses of FSH, and delayed embryo transfer during subsequent warmed cryo-preserved embryo transfer. Eligible patient have a PCO pattern in their ovaries during transvaginal ultrasound.
Eligibility Criteria
Inclusion Criteria: * PCO pattern with \> 25 antral follicles * AMH \> 3.5 Exclusion Criteria: * BMI \> 35 * body morphology making transvaginal retrieval difficult or impossible * complicating medical condition making pregnancy or IVF relatively contra-indicated
Contact & Investigator
Bruce I Rose, MD, PhD
PRINCIPAL INVESTIGATOR
Brown Fertility
Frequently Asked Questions
Who can join the NCT04149496 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 38 Years, studying Polycystic Ovary Syndrome. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04149496 currently recruiting?
Yes, NCT04149496 is actively recruiting participants. Contact the research team at brose@brownfertility.com for enrollment information.
Where is the NCT04149496 trial being conducted?
This trial is being conducted at Jacksonville, United States.
Who is sponsoring the NCT04149496 clinical trial?
NCT04149496 is sponsored by Bruce Rose, MD. The principal investigator is Bruce I Rose, MD, PhD at Brown Fertility. The trial plans to enroll 300 participants.