NCT05887440 Isokinetic Strength Training in Hemiparetic Patient With Knee Extension Thrust
| NCT ID | NCT05887440 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Rennes University Hospital |
| Condition | Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis) |
| Study Type | INTERVENTIONAL |
| Enrollment | 12 participants |
| Start Date | 2023-08-21 |
| Primary Completion | 2026-08-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 12 participants in total. It began in 2023-08-21 with a primary completion date of 2026-08-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to assess the impact of an isokinetic strength training of knee flexor and extensor muscles on walking performance in hemiparetic patients with knee extension thrust.
Eligibility Criteria
Inclusion Criteria: * Hemiparetic patient (hemorragic or ischemic stroke) * Subacute stage (\< 6 Months) ou chronic stage of stroke (\> 6 months) (6 patients in each group) * Age between 18 and 75 years * Able to walk 10 meters independently without any assistive devices * Knee extension thrust during stance phase of gait cycle (rapid posterior movement of the knee toward extension) * Scheduled rehabilitation program with isokinetic strength training * affiliation to a social security * Patients who received and signed informed consent Exclusion Criteria: * Major comprehension deficit that not allow to give informed consent and participate to isokinetic strength training (assessed with comprehension subscore of Langague screening Test) * non stable (unstable cardiovascular condition) * musculoskeletal disorders with knee pain that not allowed isokinetic strength training * Botulinum toxin injection less than 3 months or repeated injection in lower limb, * Proprioception trouble assessed with proprioception section of the Fugl-Meyer Assessment \[FMA-P\] 0/2 * spasticity of triceps surae ≥2 (Modified Ashworth scale) * ankle dorsiflexion angle less than 90° * pregnant women or breastfeeding * persons with safety measure
Contact & Investigator
Sophie HAMEAU, PhD
PRINCIPAL INVESTIGATOR
Rennes University Hospital
Frequently Asked Questions
Who can join the NCT05887440 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05887440 currently recruiting?
Yes, NCT05887440 is actively recruiting participants. Contact the research team at sophie.hameau@chu-rennes.fr for enrollment information.
Where is the NCT05887440 trial being conducted?
This trial is being conducted at Rennes, France.
Who is sponsoring the NCT05887440 clinical trial?
NCT05887440 is sponsored by Rennes University Hospital. The principal investigator is Sophie HAMEAU, PhD at Rennes University Hospital. The trial plans to enroll 12 participants.