NCT04711746 Is Clonal Hematopoiesis of Indeterminate Potential Associated With Unprovoked Pulmonary Embolism?
| NCT ID | NCT04711746 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Centre Hospitalier Universitaire, Amiens |
| Condition | Pulmonary Embolism |
| Study Type | INTERVENTIONAL |
| Enrollment | 544 participants |
| Start Date | 2021-02-01 |
| Primary Completion | 2026-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 544 participants in total. It began in 2021-02-01 with a primary completion date of 2026-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The clonal hematopoiesis of indetermined prognosis (CHIP) has been described as risk factor for juvenile atherosclerosis. Moreover, some of CHIP genes are responsible of myeloproliferative disorders. Venous thrombosis are frequent in these disorders. The purpose of this project is to determine if CHIP is frequent in unprovoked pulmonary embolism and could be part of the pathophysiology.
Eligibility Criteria
Inclusion Criteria: * For cases : Previous proximal unprovoked pulmonary embolism, negative thrombophilia screening. * For control : Previous proximal provoked pulmonary embolism, negative thrombophilia screening. Exclusion Criteria: * Age superior to 65 years old, * Active cancer
Contact & Investigator
Frequently Asked Questions
Who can join the NCT04711746 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Pulmonary Embolism. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04711746 currently recruiting?
Yes, NCT04711746 is actively recruiting participants. Contact the research team at soudet.simon@chu-amiens.fr for enrollment information.
Where is the NCT04711746 trial being conducted?
This trial is being conducted at Amiens, France.
Who is sponsoring the NCT04711746 clinical trial?
NCT04711746 is sponsored by Centre Hospitalier Universitaire, Amiens. The trial plans to enroll 544 participants.