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Recruiting NCT06851091

Investigation of the Relationship Between Central Sensitization and Balance in Fibromyalgia

Trial Parameters

Condition Fibromyalgia Syndrome
Sponsor Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Study Type OBSERVATIONAL
Phase N/A
Enrollment 75
Sex FEMALE
Min Age 18 Years
Max Age 65 Years
Start Date 2025-02-18
Completion 2025-09-04
Interventions
Biodex Balance SystemPressure Pain Threshold (PPT) Measurement with AlgometerConditioned Pain Modulation (CPM)

Brief Summary

The aim of the study is to investigate the relationship between central sensitization parameters and changes in static and dynamic balance in patients with fibromyalgia. The main questions it aims to answer are: * Do central sensitization parameters differ in patients with fibromyalgia compared to healthy individuals? * How is balance performance in these individuals compared to healthy controls? * Do central sensitization parameters affect static and dynamic balance in patients with fibromyalgia? * Do central sensitization parameters lead to quantitative changes in balance in patients with fibromyalgia?

Eligibility Criteria

Inclusion Criteria: * Diagnosis of FMS according to the ACR 2016 diagnostic criteria * Being between the ages of 18 and 65 * Being literate * Providing informed consent by signing the voluntary consent form Exclusion Criteria: * Being under 18 years old or over 65 years old * Presence of vestibular disorders * Having undergone spinal and/or extremity surgery (such as for back/hip/knee/foot) within the last 6 months * History of lower extremity amputation * Presence of spinal deformities * Peripheral arterial disease * Vitamin B12 deficiency * Any neurological disorder (e.g., stroke, traumatic brain injury, multiple sclerosis, Parkinson's disease, central nervous system malignancies, etc.) * Severe cardiopulmonary insufficiency (stage 3-4) * Uncontrolled systemic diseases such as hypertension and diabetes * Presence of systemic inflammatory diseases, malignancies, or active infections * Pregnancy

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