NCT06081946 Investigation of the Effects of Sleep Fragmentation on Itch and Pain Sensitivity
| NCT ID | NCT06081946 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Aalborg University |
| Condition | Histamine |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2023-12-15 |
| Primary Completion | 2025-09-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2023-12-15 with a primary completion date of 2025-09-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
In This experiment, the investigators would like to test following hypotheses regarding the influence of sleep fragmentation on itch: * To investigate similarity and differences between itch and pain by comparing the effect of sleep deprivation in them. * To evaluate the inflammatory state induced by sleep fragmentation via the analysis of C-reactive protein (CRP) levels from blood samples. * To correlate the anxiety and depression scores (evaluated through questionnaires) with itch and pain sensitivity and evaluate how they are affected by sleep fragmentation.
Eligibility Criteria
Inclusion Criteria: * Healthy men and women * 18-60 years * Speak and understand English * Access to a smartphone during the experimental nights Exclusion Criteria: * Pregnancy or lactation * Drug addiction defined as any use of cannabis, opioids, or other drugs * Previous or current history of neurological, dermatological, immunological musculoskeletal, cardiac disorder or mental illnesses (psychiatric diagnosis) that may affect the results (e.g., neuropathy, muscular pain in the upper extremities, anxiety, depression, schizophrenia etc.) * Moles, wounds, scars, or tattoos in the area to be treated or tested * Current use of medications that may affect the trial such as antihistamines and pain killers. * Skin diseases * Consumption of alcohol or painkillers 24 hours before the study days and between these * Acute or chronic pain and itch * Participation in other trials within 1 week of study entry (4 weeks in the case of pharmaceutical studies) * Lack of ability to cooperate
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06081946 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Histamine. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06081946 currently recruiting?
Yes, NCT06081946 is actively recruiting participants. Contact the research team at slv@hst.aau.dk for enrollment information.
Where is the NCT06081946 trial being conducted?
This trial is being conducted at Aalborg, Denmark.
Who is sponsoring the NCT06081946 clinical trial?
NCT06081946 is sponsored by Aalborg University. The trial plans to enroll 30 participants.