NCT07307846 Investigation of the Effects of Interlaminar Epidural Steroid Injection on Upper Extremity Proprioception in Patients With Chronic Cervical Radiculopathy
| NCT ID | NCT07307846 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Marmara University |
| Condition | Cervical Radiculopathy |
| Study Type | INTERVENTIONAL |
| Enrollment | 46 participants |
| Start Date | 2026-01-05 |
| Primary Completion | 2026-04-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 46 participants in total. It began in 2026-01-05 with a primary completion date of 2026-04-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Cervical radiculopathy is a common condition caused by irritation or compression of cervical nerve roots, often leading to unilateral neuropathic pain and functional impairment. Proprioceptive deficits in the upper extremity have been demonstrated in various cervical spine disorders; however, the effect of interlaminar epidural steroid injection (ILESI) on upper extremity proprioception in patients with chronic cervical radiculopathy has not been previously examined. This prospective interventional study aims to evaluate changes in upper extremity proprioception following unilateral ILESI in patients with cervical disc herniation-related chronic radiculopathy. A secondary aim is to investigate the relationship between proprioceptive changes and clinical outcomes such as pain, neuropathic pain, disability, grip strength, and quality of life.
Eligibility Criteria
Inclusion Criteria: Participants must meet all of the following: * Female or male, 18-65 years of age * Presence of unilateral cervical radicular pain lasting at least 3 months * MRI of the cervical spine within the last 12 months demonstrating at least one cervical disc herniation consistent with the patient's symptoms * Diagnosed with chronic cervical radiculopathy based on history, physical examination, and clinical evaluation * Ability to read and write (literacy) * Willingness to participate and ability to provide written informed consent Exclusion Criteria: Participants will be excluded for any of the following: * Cervical physical therapy or cervical spinal injection performed within the past 6 months * Symptoms or diagnosis of upper extremity entrapment neuropathy * Documented vitamin B12 deficiency or vitamin D deficiency on laboratory results within the past year * History of cervical spine surgery or significant cervical trauma * Bilateral cervical radicular pain * Cervical spinal stenosis * History of upper extremity surgery or significant upper extremity trauma * Cognitive impairment, major psychiatric disorder, intellectual disability, or history of significant neurological disease * Diagnosis of polyneuropathy * Diagnosis of Diabetes Mellitus * Diagnosis of fibromyalgia * Current use of medications that may impair proprioception or have sedative effects (e.g., gabapentinoids, antidepressants, muscle relaxants) * Active local or systemic infection * Coagulopathy or bleeding diathesis * Known allergy to any components of the planned injection (triamcinolone, lidocaine, saline, contrast medium) * Pregnancy * Inability or unwillingness to provide informed consent * Illiteracy (unable to read or write) Withdrawal Criteria * Voluntary withdrawal of consent at any time * Inability or unwillingness to continue study participation for any reason * New medical condition or event after enrollment that renders continuation unsafe according to the investigator's judgment
Contact & Investigator
Savaş Şencan, Assoc. Prof., Pain Medicine
STUDY DIRECTOR
Algology Division, Department of Physical Medicine and Rehabilitation, Marmara University Faculty of Medicine
Frequently Asked Questions
Who can join the NCT07307846 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Cervical Radiculopathy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07307846 currently recruiting?
Yes, NCT07307846 is actively recruiting participants. Contact the research team at gokce_cihaner@hotmail.com for enrollment information.
Where is the NCT07307846 trial being conducted?
This trial is being conducted at Pendik, Turkey (Türkiye).
Who is sponsoring the NCT07307846 clinical trial?
NCT07307846 is sponsored by Marmara University. The principal investigator is Savaş Şencan, Assoc. Prof., Pain Medicine at Algology Division, Department of Physical Medicine and Rehabilitation, Marmara University Faculty of Medicine. The trial plans to enroll 46 participants.