← Back to Clinical Trials
Recruiting NCT05122897

NCT05122897 Investigation of Biofilm Formation on Temporary push-on Rings of Implant Crowns

◆ AI Clinical Summary
Plain-language summary for patients
Clinical Trial Summary
NCT ID NCT05122897
Status Recruiting
Phase
Sponsor University Hospital, Basel, Switzerland
Condition Dental Plaque
Study Type INTERVENTIONAL
Enrollment 33 participants
Start Date 2022-01-11
Primary Completion 2026-02

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Rings made of PA (test)Rings made of TAN (control)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 33 participants in total. It began in 2022-01-11 with a primary completion date of 2026-02.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This in-vivo study investigates early (48h), mature (2 weeks) and long-term (3 months) biofilm formation and composition on temporary push-on cones (exchangeable conical rings) made of noble-alloy-based materials (Pagalinor, PA) in comparison to Titanium-6Aluminum-7Niobium alloy (TAN) presently used in the transmucosal portion of dental implant abutments.

Eligibility Criteria

Inclusion Criteria: * Informed Consent signed by the subject * Presence of one or more bone level titanium implant prior to insertion of the final restoration * No systemic illness * No heavy smoking (smoking \<10 cigarettes/day) * No pregnancy * No active periodontitis (probing pocket depth ≤4 mm) * No pharmacological treatment or antibiotic therapy during or up to three months before the study Exclusion Criteria: * Systemic illness (e.g. Diabetes) * Heavy smoking (smoking \>10 cigarettes/day) * Known or suspected non-compliance, drug or alcohol abuse * Pregnancy * Active periodontitis (probing pocket depth \>4 mm) * Pharmacological treatment or antibiotic therapy during or up to three months before the study

Contact & Investigator

Central Contact

Nicola U. Zitzmann, Prof. Dr.

✉ n.zitzmann@unibas.ch

📞 +41 61 267 26 36

Principal Investigator

Nicola U. Zitzmann, Prof. Dr.

PRINCIPAL INVESTIGATOR

University Center for Dental Medicine Basel

Frequently Asked Questions

Who can join the NCT05122897 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Dental Plaque. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05122897 currently recruiting?

Yes, NCT05122897 is actively recruiting participants. Contact the research team at n.zitzmann@unibas.ch for enrollment information.

Where is the NCT05122897 trial being conducted?

This trial is being conducted at Basel, Switzerland.

Who is sponsoring the NCT05122897 clinical trial?

NCT05122897 is sponsored by University Hospital, Basel, Switzerland. The principal investigator is Nicola U. Zitzmann, Prof. Dr. at University Center for Dental Medicine Basel. The trial plans to enroll 33 participants.

Related Trials

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology