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Recruiting NCT06728137

NCT06728137 Investigation of a New Compression Bandage System Combining Skin Protection, Padding and Compression in One Single Bandage and Comparing to an Existing One-component Bandage.

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Clinical Trial Summary
NCT ID NCT06728137
Status Recruiting
Phase
Sponsor Lohmann & Rauscher
Condition Healthy Volunteers
Study Type OBSERVATIONAL
Enrollment 25 participants
Start Date 2025-01
Primary Completion 2025-03

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 25 participants in total. It began in 2025-01 with a primary completion date of 2025-03.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this study is to learn about the pressure that can be maintained by a new compression bandage over the course of seven days in healthy volunteers. This bandage combines skin protection, padding and compression in one single bandage. It will be applied to the participants lower legs. A similar device will be applied to the other lower leg of the participant. A randomisation method is used for the assignment of the bandages to the participants legs. Researchers will compare the bandage pressures of both bandages. The so-called sub-bandage pressure will be measured at the day of application and on the next day, the third day and the last day. Participants will also be asked about the wearing comfort of both bandages.

Eligibility Criteria

Inclusion Criteria: * Healthy intact skin with no clinical signs of chronic venous insufficiency and no signs of any dermatological condition such as eczema or psoriasis as assessed by investigating physician. * Ankle circumference \> 18 cm (2 cm above ankle) as assessed by the investigating physician. Exclusion Criteria: * Known sensitivity to the study products (Rosidal 1C or Urgo K1) or any of their components * Chronic venous disease with CEAP ≥2 * Ankle Brachial Pressure Index (ABPI) \< 0.8 or \>1.3 * Ankle circumference \<18 or \> 32 cm * Venous echo-Doppler with recognizable abnormalities * History of * malignant ulcer * clinically infected wound * peripheral arterial occlusive diseases, * cardiac insufficiency or cardiac disease such as congestive heart failure, coronary artery disease, myocardial infarction, coronary artery bypass graft * cerebrovascular disease * liver or renal disease * septic phlebitis, * phlegmasia coerulea dolens, * sensation disorders of the skin * eczema, psoriasis * Use of diuretics, antihypertension or drugs that influence the capillary infiltration * Comorbidities that could affect compression therapy, particularly diseases causing oedema * Reliable severe malnutrition * Diabetes Mellitus * BMI \> 30 kg/m2 * Pregnancy or breast feeding * Participation in an interventional clinical trial within the last 3 months and during participation in this study * Participant is analphabet

Contact & Investigator

Central Contact

Christine Boehm, MD PhD

✉ Christine.Boehm@de.LRmed.com

📞 +49 2634 996144

Principal Investigator

Prof. Dr. Valentina Dini

PRINCIPAL INVESTIGATOR

Department of Clinical and Experimental Medicine, University of Pisa

Frequently Asked Questions

Who can join the NCT06728137 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Healthy Volunteers. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06728137 currently recruiting?

Yes, NCT06728137 is actively recruiting participants. Contact the research team at Christine.Boehm@de.LRmed.com for enrollment information.

Where is the NCT06728137 trial being conducted?

This trial is being conducted at Pisa, Italy.

Who is sponsoring the NCT06728137 clinical trial?

NCT06728137 is sponsored by Lohmann & Rauscher. The principal investigator is Prof. Dr. Valentina Dini at Department of Clinical and Experimental Medicine, University of Pisa. The trial plans to enroll 25 participants.

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