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Recruiting NCT07297641

Intravascular Imaging-Guided Versus Angiography- Guided PCI in Patients With DES-ISR

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Trial Parameters

Condition PCI
Sponsor Nanjing First Hospital, Nanjing Medical University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 1,500
Sex ALL
Min Age 18 Years
Max Age 80 Years
Start Date 2026-01-01
Completion 2026-11-01
Interventions
percutaneous coronary intervention

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Brief Summary

This study aimed to compare the clinical and angiographic outcomes of patients with DES-ISR who underwent repeat PCI with intravascular imaging or angiographic guidance.

Eligibility Criteria

Inclusion Criteria: (1) Patients with DES-ISR lesions; (2) Life expectancy of at least 1 year; (3) DES-ISR lesions occurring for the first time in native coronary arteries and suitable for re-PCI based on angiographic findings. Exclusion Criteria: (1) Bare-metal stent in-stent restenosis (BMS-ISR). (2) Non-DES-ISR lesions. (3) Incomplete clinical and angiographic data. (4) Poor quality of IVUS or angiographic images. (5) Recurrent DES-ISR. (6) Optical coherence tomography (OCT) guidance.

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