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Recruiting Phase 4 NCT06511232

Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction

Trial Parameters

Condition Anterior Cruciate Ligament Tear
Sponsor The Methodist Hospital Research Institute
Study Type INTERVENTIONAL
Phase Phase 4
Enrollment 84
Sex ALL
Min Age 18 Years
Max Age 40 Years
Start Date 2024-08-19
Completion 2027-07-31
Interventions
Intraosseous Morphine

Brief Summary

The purpose of this study is to determine if intraosseous (IO) morphine decreases pain and post-operative opioid use in patients undergoing anterior cruciate ligament (ACL) reconstruction.

Eligibility Criteria

Inclusion Criteria: * Patients of the IRB approved surgeon(s) undergoing ACL reconstruction with bone-to-bone (BTB) autograft * Patients aged between 18-40 years old at the time of surgery Exclusion Criteria: * Patients undergoing ACL reconstruction with any other type of autograft or allograft other than BTB * Patients younger than 18 years old or older than 40 years old * Patients undergoing meniscal root repair or any other repair that changes their weight-bearing status * Patients with a history of substance abuse * Vulnerable populations * Patients on chronic pain medication within the last 6 months * BMI \>/= 35 * Allergy to morphine * Unwilling to participate * Any additional reason the PI deems reasonable

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