NCT07108764 Intraoperative Infusion of Either Lidocaine or Dexmedetomidine on Regional Cerebral Oxygen Saturation and Postoperative Delirium in Elderly Patients Undergoing Abdominal Surgeries
| NCT ID | NCT07108764 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Tanta University |
| Condition | Intraoperative Infusion |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2025-04-17 |
| Primary Completion | 2027-04-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2025-04-17 with a primary completion date of 2027-04-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to compare the effect of intraoperative infusion of either lidocaine or dexmedetomidine on the incidence of postoperative delirium (POD) in elderly patients undergoing major surgeries. It also aims to evaluate the impact of both medications on intraoperative regional cerebral oxygen saturation (rSO₂).
Eligibility Criteria
Inclusion Criteria: * Age ≥ 65years old. * Both sexes. * Physical status classification of II - III according to the American Society of Anesthesiologists (ASA). * Undergo elective non-cardiac surgeries. Exclusion Criteria: * History of mental illness, neurological illness, or scoring less than 8 using the abbreviated mental test (AMT) before operation. * Severe hearing or visual impairment that may interfere with communication. * Severe renal or hepatic dysfunction. * Patients on central nervous system (CNS) medications (antipsychotics, anticonvulsants, antiparkinsonian, antidepressants). * Contraindications to lidocaine or dexmedetomidine \[e.g., allergy, severe bradycardia, atrioventricular (AV) block\].
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07108764 clinical trial?
This trial is open to participants of all sexes, aged 65 Years or older, studying Intraoperative Infusion. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07108764 currently recruiting?
Yes, NCT07108764 is actively recruiting participants. Contact the research team at dhamdy420@gmail.com for enrollment information.
Where is the NCT07108764 trial being conducted?
This trial is being conducted at Tanta, Egypt.
Who is sponsoring the NCT07108764 clinical trial?
NCT07108764 is sponsored by Tanta University. The trial plans to enroll 100 participants.