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Recruiting NCT07262515

Integrative Epidemiology of Prognosis in Patients With Acute Alcoholic Hepatitis at AP-HP

Trial Parameters

Condition Acute Alcoholic Hepatitis
Sponsor Assistance Publique - Hôpitaux de Paris
Study Type OBSERVATIONAL
Phase N/A
Enrollment 1,400
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2024-07-19
Completion 2025-12

Brief Summary

Acute alcoholic hepatitis (AAH) is a severe liver disease that often occurs in individuals with prolonged excessive alcohol consumption. Patients face a high risk of liver failure, complications, and death, despite available treatments. Current prognostic scores based on blood tests provide limited accuracy and do not capture the full complexity of the disease. The purpose of this study is to improve the prediction of patient outcomes after a diagnosis of acute alcoholic hepatitis. By integrating clinical, biological, and histological information collected from the AP-HP data warehouse, the investigators aim to identify more reliable prognostic markers. This could help physicians better tailor treatments and improve survival of patients affected by this condition.

Eligibility Criteria

Inclusion Criteria: * Adult patients (≥18 years) * Diagnosis of acute alcoholic hepatitis (ICD10 K701 or occurrence of the terms "HAA" (French translation of "AAH" or "hépatite alcoolique aiguë" (French translation of "acute alcoholic hepatitis") in a pathology report, followed by manual verification Exclusion Criteria: \- Patients younger than 18 years at diagnosis

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