NCT04666402 Integrated Diagnostics for Early Diagnosis of Liver Disease
| NCT ID | NCT04666402 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Manchester University NHS Foundation Trust |
| Condition | Non-Alcoholic Fatty Liver Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 1,200 participants |
| Start Date | 2020-10-21 |
| Primary Completion | 2027-03-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 1,200 participants in total. It began in 2020-10-21 with a primary completion date of 2027-03-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This is an observational study that will explore the hypothesis that by combining data from patients with liver disease with novel blood biomarkers, single nucleotide polymorphism (SNP) analysis and faecal microbiome analysis. The Investigators will improve diagnosis of liver fibrosis compared to the current available diagnostic tools.
Eligibility Criteria
Inclusion Criteria: * All patients referred to Community Liver Assessment Clinic. * Male or female \> 18 years of age. * Females will be non-pregnant and non-lactating. Exclusion Criteria: * Age \< 18 years. * Pregnancy/breast-feeding. Women of childbearing potential (not \>2 years post- menopausal and/or not surgically sterilised) must have a negative blood serum pregnancy test. * Isolated bilirubinaemia. * Known pre-existing liver disease. * Acutely unwell. * Suspected malignancy.
Contact & Investigator
Varinder Athwal
PRINCIPAL INVESTIGATOR
Manchester University NHS Foundation Trust/Manchester University
Frequently Asked Questions
Who can join the NCT04666402 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Non-Alcoholic Fatty Liver Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04666402 currently recruiting?
Yes, NCT04666402 is actively recruiting participants. Contact the research team at Varinder.athwal@manchester.ac.uk for enrollment information.
Where is the NCT04666402 trial being conducted?
This trial is being conducted at Manchester, United Kingdom.
Who is sponsoring the NCT04666402 clinical trial?
NCT04666402 is sponsored by Manchester University NHS Foundation Trust. The principal investigator is Varinder Athwal at Manchester University NHS Foundation Trust/Manchester University. The trial plans to enroll 1,200 participants.