NCT07106359 Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome
| NCT ID | NCT07106359 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Alabama at Birmingham |
| Condition | Cascade Testing |
| Study Type | INTERVENTIONAL |
| Enrollment | 185 participants |
| Start Date | 2025-09-15 |
| Primary Completion | 2027-08-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 185 participants in total. It began in 2025-09-15 with a primary completion date of 2027-08-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of the study is to see if our education materials help people at risk for Lynch syndrome decide about seeking genetic services. Untested relatives of patients with Lynch syndrome will be recruited to complete a baseline survey and will be randomized to receive either the an information letter or an information letter plus a booklet. Two follow-up surveys will be administered over the span of 6 months. Participants will also be invited to join an optional exit interview to provide feedback.
Eligibility Criteria
Probands Inclusion Criteria: * English speaking * at least 18 years old * have had genetic testing for Lynch syndrome (LS) * do not have a condition that would interfere with their ability to provide informed consent and complete study activities (e.g., cognitive dysfunction evaluated using clinical judgment during screening) Clinical Trial Participants Inclusion Criteria: * English-speaking * at least 18 years old * a blood relative of a patient who was diagnosed with LS * potentially at risk for LS * have not scheduled or had pre-test genetic counseling or genetic testing for LS * do not have a personal history of a cancer (excluding non-melanoma skin cancer) * do not have a condition that would interfere with their ability to provide informed consent and complete study activities (e.g., cognitive dysfunction evaluated using clinical judgment during screening)
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07106359 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Cascade Testing. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07106359 currently recruiting?
Yes, NCT07106359 is actively recruiting participants. Contact the research team at LSPilotStudy@uabmc.edu for enrollment information.
Where is the NCT07106359 trial being conducted?
This trial is being conducted at Birmingham, United States.
Who is sponsoring the NCT07106359 clinical trial?
NCT07106359 is sponsored by University of Alabama at Birmingham. The trial plans to enroll 185 participants.