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Recruiting Phase 2 NCT07294118

NCT07294118 Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage

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Clinical Trial Summary
NCT ID NCT07294118
Status Recruiting
Phase Phase 2
Sponsor The University of Texas Medical Branch, Galveston
Condition Subarachnoid Hemorrhage, Aneurysmal
Study Type INTERVENTIONAL
Enrollment 15 participants
Start Date 2026-01-02
Primary Completion 2027-06

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 100 Years
Study Type INTERVENTIONAL
Interventions
LidocaineLidocaine and Dexamethasone

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.

This trial targets 15 participants in total. It began in 2026-01-02 with a primary completion date of 2027-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this clinical trial is to learn if an infusion of lidocaine, with or without steroids, into the middle meningeal artery (MMA) helps relieve severe headaches in patients with spontaneous subarachnoid hemorrhage (SAH). It will also study the safety of this treatment.

Eligibility Criteria

Inclusion Criteria: * Age ≥18 years. * Diagnosed with aneurysmal SAH, Hunt and Hess Grades 1-2. * Consent to study procedures and follow-up evaluations. Exclusion Criteria: * Known allergies to lidocaine or steroids. * Arteriovenous malformations. * Dural Arteriovenous Fistulas. * Other significant intracranial pathologies. * Hemodynamic instability preventing safe intervention. * Previous MMA interventions. * Previous craniotomies or need for craniotomy. * Need for external ventricular drain.

Contact & Investigator

Central Contact

Matias Costa

✉ mlcosta@utmb.edu

📞 409-772-1011

Principal Investigator

Kan Peter, MD

PRINCIPAL INVESTIGATOR

University of Texas Medical Branch, Galveston

Frequently Asked Questions

Who can join the NCT07294118 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 100 Years, studying Subarachnoid Hemorrhage, Aneurysmal. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT07294118 trial and what does that mean for participants?

Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.

Is NCT07294118 currently recruiting?

Yes, NCT07294118 is actively recruiting participants. Contact the research team at mlcosta@utmb.edu for enrollment information.

Where is the NCT07294118 trial being conducted?

This trial is being conducted at Galveston, United States.

Who is sponsoring the NCT07294118 clinical trial?

NCT07294118 is sponsored by The University of Texas Medical Branch, Galveston. The principal investigator is Kan Peter, MD at University of Texas Medical Branch, Galveston. The trial plans to enroll 15 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology