NCT07578662 Influence of Proximal Caries on Outcome of Direct Pulp Capping in Permanent Mandibular Molars With Reversible Pulpitis
| NCT ID | NCT07578662 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Postgraduate Institute of Dental Sciences Rohtak |
| Condition | Reversible Pulpitis |
| Study Type | INTERVENTIONAL |
| Enrollment | 154 participants |
| Start Date | 2026-04-29 |
| Primary Completion | 2027-10-28 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 154 participants in total. It began in 2026-04-29 with a primary completion date of 2027-10-28.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aim of the study is to assess the Influence of proximal caries on outcome of direct pulp capping in permanent mandibular molars with sign of reversible pulpitis. objective- Primary objective- To evaluate and compare the clinical and radiographic outcome of Direct pulp capping in mandibular molars with occlusal and proximal carious lesions. Secondary objective- To evaluate and compare 1.OHRQoL after Direct pulp capping in occlusal and proximal lesion. 2. Postoperative pain, after Direct pulp capping in occlusal and proximal lesion Subjects of age group 15 - 40 yrs will be included and divided into two groups 1) Permanent mature molars with proximal carious lesion 2)Permanent mature molars with occlusal carious lesion.
Eligibility Criteria
Inclusion Criteria: 1. Mature permanent mandibular molars with extremely deep caries that penetrate the entire thickness of dentine as detected on radiograph with reversible pulpitis will be included. 2. Participant with Reversible pulpitis will be diagnosed clinically based on discomfort experienced by the participant when a stimulus such as cold or sweet is applied and goes away within a couple of seconds following the removal of the stimulus, with no significant radiographic changes in the periapical region of the suspect tooth and the pain experienced is not spontaneous. 3. The pulpal sensibility will be confirmed through positive response to electric and cold tests (Endo frost) and the presence of bleeding after caries excavation. 4.Pulpal and the periapical diagnosis will be established based on the diagnostic terminology approved by American Association of Endodontists (AAE, 2019). 5.Teeth with a negative response to palpation and percussion testing and radiographic finding of periapical index (PAI) score ≤2 and healthy periodontium (probing pocket depth ≤3 mm and mobility within normal limit) will be included. 6.Teeth in which hemostasis achieved within 5 mins will be included. 7.Only pulp exposures with size 0.5-1 mm will be included \- Exclusion Criteria: 1. Mechanical or pulp exposure due to trauma 2. absence of exposure after excavation of caries 3. failure to achieve hemostasis within 5 mins 4. irreversible pulpitis and teeth having periapical lesions 5. periodontal disease, resorptive defects, calcified canals, as assessed by radiographic examination will serve as criteria for exclusion. 6. Also immunocompromised, Pregnant and subjects having systemic diseases will be excluded -
Contact & Investigator
Dr. Pankaj Sangwan, MDS
PRINCIPAL INVESTIGATOR
PGIDS, Rohtak, 124001
Frequently Asked Questions
Who can join the NCT07578662 clinical trial?
This trial is open to participants of all sexes, aged 15 Years or older, up to 40 Years, studying Reversible Pulpitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07578662 currently recruiting?
Yes, NCT07578662 is actively recruiting participants. Contact the research team at drps_1@yahoo.co.in for enrollment information.
Where is the NCT07578662 trial being conducted?
This trial is being conducted at Rohtak, India.
Who is sponsoring the NCT07578662 clinical trial?
NCT07578662 is sponsored by Postgraduate Institute of Dental Sciences Rohtak. The principal investigator is Dr. Pankaj Sangwan, MDS at PGIDS, Rohtak, 124001. The trial plans to enroll 154 participants.