NCT05960331 Influence of Autonomy on Motor Learning in People With Parkinson's Disease
| NCT ID | NCT05960331 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National Taiwan University Hospital |
| Condition | Parkinson Disease |
| Study Type | INTERVENTIONAL |
| Enrollment | 72 participants |
| Start Date | 2023-08-21 |
| Primary Completion | 2025-07-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 72 participants in total. It began in 2023-08-21 with a primary completion date of 2025-07-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to explore the benefits of autonomy supported learning in patients with Parkinson's disease. The main questions to answer are: * Whether autonomy supported learning can benefit motor learning in PD patients * Whether autonomy supported learning can enhance intrinsic motivation and/ or information processing of PD patients in learning a new task. * Whether autonomy supported learning can facilitate cortical excitability change after practicing a new task. Participants will be recruited into two groups (Self-control group, SC; and yoked group, YK) to learn a finger-pressing trajectory matching task * Participants in SC group will have choice over feedback schedule during trial practice * Participants in YK group will receive feedback with no-choice during trial practice Researchers will compare the retention test performance to see if autonomy supported learning will lead to better learning effect.
Eligibility Criteria
Inclusion Criteria: * age above 20-years-old * able to follow instructions to perform the tasks (Montreal Cognitive Assessment ≥ 24) * no surgery and injury in upper extremities in recent 6 months Exclusion Criteria: * other neurological disorders in addition to Parkinson's disease * Parkinson's disease dementia * symptom of severe tremor in upper extremities (score ≥ 3 in Question 15 to 18 of UPDRS-III) * deep brain stimulation or pacemaker implanted * medical history of seizure * a blood-relative with history of epilepsy * unstable medical conditions * pregnancy
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05960331 clinical trial?
This trial is open to participants of all sexes, aged 20 Years or older, studying Parkinson Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05960331 currently recruiting?
Yes, NCT05960331 is actively recruiting participants. Contact the research team at yayunlee@ntu.edu.tw for enrollment information.
Where is the NCT05960331 trial being conducted?
This trial is being conducted at Taipei, Taiwan.
Who is sponsoring the NCT05960331 clinical trial?
NCT05960331 is sponsored by National Taiwan University Hospital. The trial plans to enroll 72 participants.
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