NCT07104084 Influence of Antiseptic Washes on Wound Healing Complications After THA
| NCT ID | NCT07104084 |
| Status | Recruiting |
| Phase | — |
| Sponsor | F. Johannes Plate |
| Condition | Hip Osteoarthritis |
| Study Type | INTERVENTIONAL |
| Enrollment | 420 participants |
| Start Date | 2025-10-09 |
| Primary Completion | 2027-09-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 420 participants in total. It began in 2025-10-09 with a primary completion date of 2027-09-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this research trial is to evaluate the effect of two types of washing solutions on wound healing after total hip replacement surgery. Washing solutions are used routinely during total hip replacements to clean the wound after the components have been placed and the wound is about to be closed with sutures. It is currently not known which washing solution may be better for wound healing and whether a certain solution decreases the risk of wound healing complications after total hip replacement. Therefore, this research trial is being conducted. Study participants will be randomized into one of two groups: washing the surgical wound with povidone-iodine solution (Surgiphor, Becton Dickinson, Franklin Lakes, NJ) or chlorhexidine solution (Irrisept, Irrimax Corporation, Lawrenceville, GA). All patients will undergo standard of care total hip replacements without any other change in surgery. The best type of solution that cleans the wound and potentially leads to better wound healing is unknown. This study will evaluate whether there is difference in surgical wound healing between the two washing solutions. The study will pay for the washing solutions. Patients will follow up for standard postoperative visits. At the 2-week and 6-week visits, pictures of the surgical incision will be taken and saved in the electronic medical record and evaluated in a standardized way for healing of the incision and the appearance of the scar. Postoperative complications and returns to the hospital or additional surgeries will be collected from the electronic medical record.
Eligibility Criteria
Inclusion Criteria: * osteoarthritis or avascular necrosis of the femoral head, failed conservative management, indicated for total hip replacement Exclusion Criteria: * reported or documented allergy to chlorhexidine or povidone-iodine
Contact & Investigator
Frank J Plate, MD, PhD
PRINCIPAL INVESTIGATOR
University of Pittsburgh
Frequently Asked Questions
Who can join the NCT07104084 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Hip Osteoarthritis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07104084 currently recruiting?
Yes, NCT07104084 is actively recruiting participants. Contact the research team at platefj2@upmc.edu for enrollment information.
Where is the NCT07104084 trial being conducted?
This trial is being conducted at Monroeville, United States, Pittsburgh, United States.
Who is sponsoring the NCT07104084 clinical trial?
NCT07104084 is sponsored by F. Johannes Plate. The principal investigator is Frank J Plate, MD, PhD at University of Pittsburgh. The trial plans to enroll 420 participants.