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Recruiting Phase 4 NCT07135453

NCT07135453 Induction of Cross-protective Antibodies for Serogroup 33 by Pneumococcal Conjugate Vaccines

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Clinical Trial Summary
NCT ID NCT07135453
Status Recruiting
Phase Phase 4
Sponsor University of Alabama at Birmingham
Condition Vaccine
Study Type INTERVENTIONAL
Enrollment 70 participants
Start Date 2026-07
Primary Completion 2027-03

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Pneumococcal Vaccine

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 4 studies follow an already-approved treatment in real-world conditions to monitor long-term safety and effectiveness.

This trial targets 70 participants in total. It began in 2026-07 with a primary completion date of 2027-03.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this study is to learn whether different types of vaccines to prevent bacterial infections are able to effectively create antibodies that defend against certain types of bacteria. We will give two different types of vaccine and evaluate the effectiveness of antibodies produced by each vaccine in killing bacteria.

Eligibility Criteria

Inclusion Criteria: * Healthy adult Exclusion Criteria: * No prior history of pneumococcal vaccination * No immunosuppressing medications or chronic diseases that affect immune function

Contact & Investigator

Central Contact

David LaFon, MD

✉ dlafon@uabmc.edu

📞 2059343411

Frequently Asked Questions

Who can join the NCT07135453 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Vaccine. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT07135453 trial and what does that mean for participants?

Phase 4 studies are conducted after a treatment has been approved. They monitor long-term safety and real-world effectiveness in a broader patient population.

Is NCT07135453 currently recruiting?

Yes, NCT07135453 is actively recruiting participants. Contact the research team at dlafon@uabmc.edu for enrollment information.

Where is the NCT07135453 trial being conducted?

This trial is being conducted at Birmingham, United States.

Who is sponsoring the NCT07135453 clinical trial?

NCT07135453 is sponsored by University of Alabama at Birmingham. The trial plans to enroll 70 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology