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Recruiting NCT06678295

Individual Factors of CBT Underlying Success

Trial Parameters

Condition Social Anxiety Disorder
Sponsor University of Washington
Study Type INTERVENTIONAL
Phase N/A
Enrollment 160
Sex ALL
Min Age 18 Years
Max Age 45 Years
Start Date 2024-10-15
Completion 2028-09-30
Interventions
Cognitive Behavioral Therapy

Brief Summary

The purpose of this study is to understand why some individuals respond fully to cognitive behavioral therapy and others do not, based on multiple sources of data such as neural, neurocognitive, clinical, and self-report data.

Eligibility Criteria

Inclusion Criteria: Clinical sample (N=110): 1. Men and women, age 18-45 2. Treatment-seeking individuals who meet criteria for a primary DSM-5 diagnosis of primary social anxiety disorder (SAD) or body dysmorphic disorder (BDD) based on the SCID-5-RV 3. Fluent in English and willing to provide informed consent. Control sample (N=50): 1. Men and women, age 18-45 2. No current or lifetime history of psychiatric disorders, as assessed using the SCID-5-RV 3. Meet criteria for low levels of anxiety (GAD-7 score of \<8) and depression (PHQ-9 score \<10) 4. Fluent in English and willing to provide informed consent Exclusion Criteria: All groups: 1. Score \< 80 based on WRAT5 Word Reading Subtest 2. fMRI contraindications (e.g., electronic medical devices such as pacemakers, implanted defibrillators, etc.; metal implants not approved for MRI; pregnancy; claustrophobia) 2\. Active suicidal or homicidal ideation, or any features requiring a higher level of care 3. Lifetime history of manic or h

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