NCT04493996 Increasing Preoperative Cognitive Reserve to Prevent Postoperative Cognitive Dysfunction in Cardiac Surgical Patients
| NCT ID | NCT04493996 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Heart and Brain Research Group, Germany |
| Condition | Postoperative Cognitive Decline |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2020-08-14 |
| Primary Completion | 2026-03 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2020-08-14 with a primary completion date of 2026-03.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Postoperative delirium (POD) and postoperative cognitive decline (POCD) can be observed after cardiosurgical interventions. Taken together, these postoperative neurocognitive dysfunctions contribute to increased morbidity and mortality and higher economic costs. Preoperative risk factors of postoperative neurocognitive dysfunctions, such as decreased neuropsychometric performance or decreased cognitive daily activities, can be interpreted as reduced cognitive reserve. The aim of this study is to build up cognitive reserves to protect against the development of POD and POCD through preoperative, home-based, cognitive training.
Eligibility Criteria
Inclusion Criteria: * Elective cardiac surgery (coronary artery bypass surgery, aortic or mitral valve replacement/reconstruction, or combination surgery) with standardized extracorporeal circulation * A sufficiently good knowledge of German is necessary as cognitive training and neuropsychological tests are language-dependent Exclusion Criteria: * History of stroke and preexisting psychiatric or neurological disorders that may impair the neuropsychological performance
Contact & Investigator
Marius Butz, Dipl.-Psych.
PRINCIPAL INVESTIGATOR
Department of Cardiac Surgery, Kerckhoff Clinic Bad Nauheim
Frequently Asked Questions
Who can join the NCT04493996 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Postoperative Cognitive Decline. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04493996 currently recruiting?
Yes, NCT04493996 is actively recruiting participants. Contact the research team at m.butz@kerckhoff-klinik.de for enrollment information.
Where is the NCT04493996 trial being conducted?
This trial is being conducted at Bad Nauheim, Germany.
Who is sponsoring the NCT04493996 clinical trial?
NCT04493996 is sponsored by Heart and Brain Research Group, Germany. The principal investigator is Marius Butz, Dipl.-Psych. at Department of Cardiac Surgery, Kerckhoff Clinic Bad Nauheim. The trial plans to enroll 100 participants.