NCT07443345 Incidence of Postoperative Diaphragmatic Dysfunction in Pregnant Women With Preeclampsia
| NCT ID | NCT07443345 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Cairo University |
| Condition | Preecalmpsia |
| Study Type | OBSERVATIONAL |
| Enrollment | 52 participants |
| Start Date | 2026-03-09 |
| Primary Completion | 2026-12-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 52 participants in total. It began in 2026-03-09 with a primary completion date of 2026-12-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Preeclampsia with severe features remains a leading contributor to maternal morbidity and mortality, particularly in low- and middle-income countries. It is defined by hypertension and involvement of multiple organ systems, including renal, hepatic, hematologic, and neurologic pathways. The interplay of endothelial dysfunction, capillary leakage, and disrupted fluid balance in these patients increases their susceptibility to perioperative pulmonary complications. Although respiratory complications in preeclampsia are clinically significant, the true incidence of postoperative diaphragmatic dysfunction in women with severe disease is not well established. Existing literature largely emphasizes general respiratory failure, pulmonary edema, or the need for mechanical ventilation, rather than specifically evaluating diaphragmatic performance with objective methods such as ultrasound. The current study sought to determine the incidence and identify risk factors for postoperative diaphragmatic dysfunction in women with severe preeclampsia following cesarean delivery.
Eligibility Criteria
Inclusion Criteria: * Patients with severe preeclampsia undergoing cesarean section * Gestational age \> 32 weeks Exclusion Criteria: * • Age \< 20 years. * Diabetic * Patients with neuromuscular diseases. * Patient refusal. * Contraindications to magnesium sulphate administration * Inability to obtain adequate ultrasound views
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07443345 clinical trial?
This trial is open to female participants only, aged 20 Years or older, up to 40 Years, studying Preecalmpsia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07443345 currently recruiting?
Yes, NCT07443345 is actively recruiting participants. Contact the research team at minaadolf1988@cu.edu.eg for enrollment information.
Where is the NCT07443345 trial being conducted?
This trial is being conducted at Cairo, Egypt.
Who is sponsoring the NCT07443345 clinical trial?
NCT07443345 is sponsored by Cairo University. The trial plans to enroll 52 participants.