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Recruiting NCT07388901

In Vivo Study on the Material Properties of iRoot SP and nRoot SP Root Canal Sealers

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Trial Parameters

Condition Chronic Apical Periodontitis
Sponsor The Dental Hospital of Zhejiang University School of Medicine
Study Type INTERVENTIONAL
Phase N/A
Enrollment 160
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2025-05-27
Completion 2026-01-31
Interventions
iRoot SPnRoot SP

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Brief Summary

A randomized controlled trial was conducted to compare the treatment efficacy of iRoot SP and nRoot SP Root Canal Sealer Materials in patients with chronic apical periodontitis.

Eligibility Criteria

Inclusion Criteria: * Age ≥ 18 years. * Diagnosis of apical periodontitis conforming to the diagnostic criteria in Endodontics. * The affected tooth is deemed restorable upon evaluation, with non-vital pulp requiring extirpation. * The affected tooth is a single tooth with a fully developed apical foramen. * No root resorption and no significant morphological variation of the root canal. * The affected tooth is undergoing primary root canal treatment. * Periapical radiolucency with a diameter of 1-5 mm and no peripheral sclerotic border observed on preoperative radiographs. * Patient is in normal mental state, conscious, and capable of normal communication. * Patient has provided informed consent. Exclusion Criteria: * Patients with alveolar bone loss exceeding one-third of the root length. * Affected teeth with root fracture, root canal obstruction, calcification, or root surface caries. * Patients with severe systemic diseases (e.g., osteoporosis, mental disorders, hepatic or renal i

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