NCT05720936 In-hospital Stellate Ganglion Block for Arrhythmic Storm
| NCT ID | NCT05720936 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Fondazione IRCCS Policlinico San Matteo di Pavia |
| Condition | Arrhythmic Storm |
| Study Type | OBSERVATIONAL |
| Enrollment | 500 participants |
| Start Date | 2017-11-07 |
| Primary Completion | 2028-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 500 participants in total. It began in 2017-11-07 with a primary completion date of 2028-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Arrhythmic storm is a real emergency and its treatment could be challenging. Antiarrhythmic drugs are few and often ineffective. Neuromodulation has been grown in evidences but no large multicentric studies are present in literature about safety and effectiveness of Percutaneous Stellate Ganglion Block (PSGB). Patients with an electrical storm refractory to at least one antiarrhythmic drug will receive PSGB and will be enrolled in the present study. The number of defibrillations before and after the treatment will be compared, complications will be annotated.
Eligibility Criteria
Inclusion Criteria: * age ≥ 18 years, * presence of arrhythmic storm defined as more than three sustained ventricular arrhythmias in 24 hours refractory to the standard medical treatment. Exclusion Criteria: * A previous history of cardiac sympathicectomy * Having a neck judged unsuitable for the procedure (previous neck surgery, previous burns, presence of large scars, thyroid goiter) Both the two approaches present in literature and commonly used for this technique are allowed for the study: * The "anatomical" approach which consist in the identification of the Chassaignac's tubercle that represents the point of needle insertion * The "echo-guided" approach Regardless to the approach (anatomical or echo-guided) the doctor will be able to choose, according to the clinical characteristics of the patients, whether to perform a single shot injection of anesthetic or a continuous infusion of anesthetic. In the second case a catheter will be left in place and connected to an infusion pump.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05720936 clinical trial?
This trial is open to participants of all sexes, studying Arrhythmic Storm. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05720936 currently recruiting?
Yes, NCT05720936 is actively recruiting participants. Contact the research team at s.savastano@smatteo.pv.it for enrollment information.
Where is the NCT05720936 trial being conducted?
This trial is being conducted at Alessandria, Italy, Bentivoglio, Italy, Bologna, Italy, Pavia, Italy and 11 additional locations.
Who is sponsoring the NCT05720936 clinical trial?
NCT05720936 is sponsored by Fondazione IRCCS Policlinico San Matteo di Pavia. The trial plans to enroll 500 participants.