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Recruiting NCT04798898

NCT04798898 Improving Survival of COlorectal LIver Metastases by RFA-mediated Immunostimulation

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Clinical Trial Summary
NCT ID NCT04798898
Status Recruiting
Phase —
Sponsor University of Aarhus
Condition Liver Metastasis Colon Cancer
Study Type INTERVENTIONAL
Enrollment 200 participants
Start Date 2022-11-14
Primary Completion 2025-06-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 99 Years
Study Type INTERVENTIONAL
Interventions
RFA (radiofrequency ablation)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 200 participants in total. It began in 2022-11-14 with a primary completion date of 2025-06-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

To examine radio frequency ablation as a treatment supplement to stimulate immunogenicity and improve survival for patients undergoing curative-intent surgery for colorectal liver metastases.

Eligibility Criteria

Inclusion Criteria: * Patients with colorectal liver metastases planned for resection * At least one tumor size \>=3cm * Performance status 0-1 Exclusion Criteria: * Liver cirrhosis * Extrahepatic metastases that can not be addressed curatively * Other malignant diseases within 5 years prior to diagnosis * Prior RFA treatment

Contact & Investigator

Central Contact

Jakob Kirkegård, MD, PhD

✉ jakob.kirkegaard@auh.rm.dk

📞 +4524995027

Principal Investigator

Frank V Mortensen, MD, DMSc

PRINCIPAL INVESTIGATOR

Aarhus University Hospital

Frequently Asked Questions

Who can join the NCT04798898 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 99 Years, studying Liver Metastasis Colon Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04798898 currently recruiting?

Yes, NCT04798898 is actively recruiting participants. Contact the research team at jakob.kirkegaard@auh.rm.dk for enrollment information.

Where is the NCT04798898 trial being conducted?

This trial is being conducted at Aarhus, Denmark.

Who is sponsoring the NCT04798898 clinical trial?

NCT04798898 is sponsored by University of Aarhus. The principal investigator is Frank V Mortensen, MD, DMSc at Aarhus University Hospital. The trial plans to enroll 200 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology