NCT06980701 Improving Oral and Systemic Health in Individuals With Prediabetes Through Personalized Oral Hygiene Advice Provided by Dentists or by AI
| NCT ID | NCT06980701 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The University of Hong Kong |
| Condition | Gum Disease |
| Study Type | INTERVENTIONAL |
| Enrollment | 148 participants |
| Start Date | 2025-04-12 |
| Primary Completion | 2026-04-18 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 148 participants in total. It began in 2025-04-12 with a primary completion date of 2026-04-18.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Prediabetes is an intermediate stage before the development of diabetes, characterized by elevated blood glucose levels but lower than the diagnostic criteria of diabetes and is associated with multiple long-term complications. This systemic disease is mutually linked to inflammatory gum diseases through circulating inflammatory mediators. Controlling inflammatory gum diseases improves blood glucose levels and reduces long-term complications. While maintaining good oral hygiene through home care is essential for managing inflammatory gum diseases, close supervision of patients' home care is labor-intensive and expensive. Artificial Intelligence (AI) has been used to provide personalized advice on the adequacy of patients' home care (oral hygiene). The investigators hypothesize that the use of AI can improve home care, thereby enhancing both gum health and systemic health, similar to human dental professionals.
Eligibility Criteria
Inclusion Criteria: * \- Subjects who are \>18 years of age and able to give informed consent. * \- Subjects who are mentally and cognitively healthy. * \- Subjects who have at least 6 anterior maxillary or mandibular natural teeth including incisors and canine. * \- Subjects who are with prediabetic state with impaired HbA1c 5.7% to 6.4%, impaired fasting plasma glucose level 5.6mmol/L to 6.9 mmol/L and/or impaired plasma glucose level after 2h OGTT 7.8 mmol/L to 11.0 mmol/L. * \- Subjects who can speak, read, or understand Cantonese to complete the satisfaction questionnaire. * \- Subjects who can practice oral hygiene procedure (regular tooth brushing and interdental cleansing/flossing/brushing) daily on their own independently. Exclusion Criteria: * \- Subjects who have less than 6 anterior maxillary or mandibular natural teeth with or without dental prostheses in those area. * \- Subjects who are with a current diagnosis or clinical history of T2DM. * \- Subjects who have mental illness, or similar problems that unable to complete the satisfaction questionnaire. * \- Subjects who cannot perform oral hygiene procedure (regular tooth brushing and interdental cleansing/flossing/brushing) by any condition of oral cavity such as tumor or maxillomandibular fixation.
Contact & Investigator
Walter Y.H. Lam, Prof.
PRINCIPAL INVESTIGATOR
The University of Hong Kong
Frequently Asked Questions
Who can join the NCT06980701 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Gum Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06980701 currently recruiting?
Yes, NCT06980701 is actively recruiting participants. Contact the research team at retlaw@hku.hk for enrollment information.
Where is the NCT06980701 trial being conducted?
This trial is being conducted at Hong Kong, Hong Kong.
Who is sponsoring the NCT06980701 clinical trial?
NCT06980701 is sponsored by The University of Hong Kong. The principal investigator is Walter Y.H. Lam, Prof. at The University of Hong Kong. The trial plans to enroll 148 participants.