NCT07171255 Improving Exercise Adherence With App Technology for At-Risk Adults Living in Rural Kansas and Nebraska
| NCT ID | NCT07171255 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Creighton University |
| Condition | Sedentary Middle Age and Older Aged Adults |
| Study Type | INTERVENTIONAL |
| Enrollment | 54 participants |
| Start Date | 2025-08-22 |
| Primary Completion | 2026-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 54 participants in total. It began in 2025-08-22 with a primary completion date of 2026-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Alzheimer's disease and related dementias are a public health crisis impacting individuals across the world. In the United States, adults living in rural areas face an elevated risk for cognitive impairment mainly due to disparities in care, higher sedentary behavior, and reduced education. This project proposes to assess the impact of a remotely delivered exercise program (i.e., RemoteEx+) through a smartphone application. The app is programmed by our team and provides video demonstrations of exercises, workout regimes, motivational messaging, and weekly ADRD risk reduction education. The project aims to assess with a pre/post design the following aims: * Aim 1. Assess the RemoteEx+ intervention exercise adherence, efficacy, enjoyment, and quality of life. We hypothesize that rural adults will report high exercise adherence (80% of session adherence), efficacy (\>50% on Self Efficacy for Exercise), and enjoyment (\>5.0 on Intrinsic Motivation Inventory - Interest / Enjoyment Subscale) and that these variables will be positively correlated with quality of life scores (36-Item Short Form Health Survey \[SF-36\]) * Aim 2. Determine the impact of a technology-driven exercise program on blood pressure and functional mobility associated with dementia risk. We hypothesize that the exercise program will result in improvements in blood pressure and functional mobility (2-minute step test and 30-second chair rise test) and that participants with high exercise adherence will see the greatest improvements in biomarkers associated with reduced dementia risk. * Aim 3. Reduce health disparities among rural-dwelling Nebraska and Kansas residents. We hypothesize that RemoteEx+ will reduce barriers to exercise (Barriers to Being Active Quiz and improve knowledge surrounding dementia and modifiable risk factors (Dementia Knowledge Assessment Tool - Version 2 \[DKAT2\]) that will result in fewer lifestyle-related health disparities for the communities involved in this study. The results from this project will inform whether RemoteEx+ has an impact on the stated outcomes above for adults living in rural areas.
Eligibility Criteria
Inclusion Criteria: * Age 40-85 years * Characterized as underactive by the Telephone Assessment of Physical Activity (TAPA)50 * Self-reported proficiency in English * Own a smartphone and willing to download an application * Primary care provider clearance to participate for those who do not pass the PAR-Q+51 * Live in a rural area (Rural-Urban Commuting Area \[RUCA\] Codes) 52 Exclusion Criteria: * Contraindications to high-intensity exercise * Cognitive impairment (\<19 on the Telephone Montreal Cognitive Assessment \[MoCA\]) * Neurodegenerative or acute neurological diagnoses (e.g., Parkinson's disease, stroke, traumatic brain injury) * Orthopedic surgery or injuries in the last 6 months
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07171255 clinical trial?
This trial is open to participants of all sexes, aged 40 Years or older, up to 85 Years, studying Sedentary Middle Age and Older Aged Adults. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07171255 currently recruiting?
Yes, NCT07171255 is actively recruiting participants. Contact the research team at rashellehoffman@creighton.edu for enrollment information.
Where is the NCT07171255 trial being conducted?
This trial is being conducted at Emporia, United States, Omaha, United States.
Who is sponsoring the NCT07171255 clinical trial?
NCT07171255 is sponsored by Creighton University. The trial plans to enroll 54 participants.