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Recruiting NCT06835738

Implementation of Multiple Micronutrient Supplementation (MMS) for Pregnant Women in Uganda

Trial Parameters

Condition Nutrient Deficiency
Sponsor Johns Hopkins Bloomberg School of Public Health
Study Type INTERVENTIONAL
Phase N/A
Enrollment 4,077
Sex ALL
Min Age 0 Years
Max Age 80 Years
Start Date 2025-06-18
Completion 2026-06-30
Interventions
Multiple Micronutrient Supplement (MMS) - dispensed in six 30-count bottlesMultiple Micronutrient Supplement (MMS) - dispensed in one 180-count bottleMultiple Micronutrient Supplement (MMS) - dispensed in two 90-count bottles

Brief Summary

The objective of this research is to understand how antenatal multiple micronutrient supplements (MMS) can be effectively implemented and scaled within the Uganda national health system context to support improved maternal nutrition and birth outcomes. Formative research has been conducted to design the implementation strategies that will be tested in this second phase of the study. The objectives are to: * Describe the implementation of the MMS intervention (which consists of MMS product, a social behavior change communication (SBCC) strategy, capacity building, MMS supply chain support, monitoring, and evaluation) and explore acceptability, feasibility, fidelity, coverage, and potential for sustainability. * Determine the effect of dispensing MMS in different bottle counts on MMS adherence and ANC attendance among pregnant women. * Determine the cost and budget impact of MMS intervention implementation integrated in the Ugandan ANC service delivery system

Eligibility Criteria

Inclusion Criteria for Pregnant women- Enrolled for follow-up throughout pregnancy (sample 1) * ≤24 weeks of amenorrhea/gestation as verified by health professionals * Attending first ANC visit at government or PNFP health facilities. * Accepted to take MMS at first ANC visit Exclusion Criteria for Pregnant women- Enrolled for follow-up throughout pregnancy (sample 1) * Pregnant women with pre-existing hematological conditions such as sickle cell anemia, thalassemia, hemochromatosis. * Pregnant women planning to relocate outside the study district during the study period. Inclusion Criteria for Pregnant women / Women that have recently delivered (single contact) (sample 2) * Currently pregnant woman or a woman who is not more than 8 weeks postpartum. * Received MMS at an ANC visit at least 3 months ago or more. * Attended at least any 2 monthly ANC visits. * Attending/attended ANC at government or private-not-for-profit health facility. Exclusion Criteria for Pregnant women / Women tha

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