Impact of Two Dietary Interventions on Simple Carbohydrate Intolerance
Trial Parameters
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Brief Summary
In this project we want to assess impact of dietary fructose as a simple sugar intolerance on abdominal pain and compare a low FODMAP diet versus an added sugar elimination diet effectiveness on symptoms but also impact on microbiome and its metabolome.
Eligibility Criteria
Inclusion Criteria: * Age: 5- 18-year-old * BMI: within normal range for age * Positive fructose breath test performed as part of diagnostic work up for abdominal pain * Willingness to consume low FODMAP and Limited Added sugar diet trial and collect required samples Exclusion Criteria: * Age: not within range * BMI: not within range * Negative fructose breath test * Any known or suspected intestinal disorder including but not limited to IBD, IBS, celiac disease, Crohn's Disease, food sensitivities, food allergies, significant by-choice food restrictions * Hormonal disorders * Use of chronic medications including contraceptives (both oral and subcutaneous), non-hormone secreting IUD- accepted * Use of oral or IV antibiotics in the last three months * Daily probiotic use (pill form) * Daily multi-vitamin except vitamin D supplements