NCT06887101 Impact of Stress on Cardiovascular Events in Patients with Peripheral Arterial Disease
| NCT ID | NCT06887101 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital, Essen |
| Condition | Peripheral Arterial Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 300 participants |
| Start Date | 2023-04-21 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 300 participants in total. It began in 2023-04-21 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Atherosclerotic cardiovascular disease is the leading cause of morbidity and mortality worldwide. Patients with peripheral arterial disease are at increased risk suffering from major adverse cardiac and limb events. Acute and chronic stress affect the cardiovascular system. Long-term negative stressors lead to cardiovascular diseases and can aggravate already existing cardiovascular diseases. However, current guidelines on cardiovascular disease prevention highlight stress as a cardiovascular risk factor there is a lack of consensus about the definition and measurement of stress. The aim of the proposed trial is to evaluate different stress measuring methods in patients with PAD depending on the occurrence of cardiovascular events.
Eligibility Criteria
Inclusion Criteria: Diagnosis of lower extremity PAD based on: * Limb bypass surgery or * aorta-femoral bypass surgery or * percutaneous transluminal angioplasty revascularization of the iliac or infrainguinal arteries or * limb or foot amputation for arterial vascular disease or * intermittent claudication and one or more of either an ankle brachial index (ABI) of less than 0.90 or a peripheral artery stenosis (≥50%) documented by angiography or duplex ultrasound or carotid revascularization or asymptomatic carotid artery stenosis of at least 50% diagnosed by duplex ultrasound or angiography Exclusion Criteria: * atrial fibrillation * high premature ventricular contractions burden * pacemaker with constant ventricular pacing * antiarrhythmic drugs class I or III
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06887101 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Peripheral Arterial Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06887101 currently recruiting?
Yes, NCT06887101 is actively recruiting participants. Contact the research team at julia.lortz@uk-essen.de for enrollment information.
Where is the NCT06887101 trial being conducted?
This trial is being conducted at Essen, Germany.
Who is sponsoring the NCT06887101 clinical trial?
NCT06887101 is sponsored by University Hospital, Essen. The trial plans to enroll 300 participants.