NCT04469439 Impact of Sinus Surgery on Individuals With Cystic Fibrosis
| NCT ID | NCT04469439 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of California, Los Angeles |
| Condition | Chronic Rhinosinusitis (Diagnosis) |
| Study Type | OBSERVATIONAL |
| Enrollment | 170 participants |
| Start Date | 2020-07-01 |
| Primary Completion | 2027-01-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 170 participants in total. It began in 2020-07-01 with a primary completion date of 2027-01-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS). Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group. Outcomes analyzed will include pulmonary, quality of life, and others.
Eligibility Criteria
Inclusion Criteria: 1. Subjects between the ages of 18 years old (inclusive) and 99 years old (inclusive, subjects over the age of 89 will be recorded to be 89 years old). 2. Diagnosed with cystic fibrosis as established by genetic testing combined with clinical assessment and/or sweat chloride 3. Diagnosed with chronic rhinosinusitis by multidisciplinary sinusitis guidelines 4. chronic rhinosinusitis symptoms persisting beyond initial medical treatment 5. Counseled for endoscopic sinus surgery and ongoing medical therapy with each patient electing their preferred treatment Exclusion Criteria: 1. Underwent endoscopic sinus surgery in past 12 months 2. Will obtain follow up care at non-participating institutions 3. Unable to complete follow-up surveys
Contact & Investigator
Daniel M Beswick, MD
PRINCIPAL INVESTIGATOR
University of California, Los Angeles
Frequently Asked Questions
Who can join the NCT04469439 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 99 Years, studying Chronic Rhinosinusitis (Diagnosis). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04469439 currently recruiting?
Yes, NCT04469439 is actively recruiting participants. Contact the research team at dbeswick@mednet.ucla.edu for enrollment information.
Where is the NCT04469439 trial being conducted?
This trial is being conducted at Los Angeles, United States, Stanford, United States, Aurora, United States, Denver, United States and 5 additional locations.
Who is sponsoring the NCT04469439 clinical trial?
NCT04469439 is sponsored by University of California, Los Angeles. The principal investigator is Daniel M Beswick, MD at University of California, Los Angeles. The trial plans to enroll 170 participants.