NCT07002710 Impact of Persistent Inflammation-Immunosuppression-Catabolism Syndrome (PICS) on the Respiratory Physiology in Patients With Prolonged Mechanical Ventilation
| NCT ID | NCT07002710 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National Taiwan University Hospital |
| Condition | PICS |
| Study Type | OBSERVATIONAL |
| Enrollment | 40 participants |
| Start Date | 2025-03-18 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 40 participants in total. It began in 2025-03-18 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Past research on PICS has mainly focused on the predictability and prognosis of PICS occurrence in ICU patients. Still, there is currently insufficient research on the role of PICS in the care setting of patients who have stabilized and are transferred to respiratory care units such as Respiratory Care Centers (RCCs) for weaning attempts. To understand the impact of PICS on the respiratory physiology of patients undergoing weaning from prolonged mechanical ventilation, investigators propose a one-year research plan
Eligibility Criteria
Inclusion Criteria: * Patients are still receiving ventilator support when transferred to the ward where the study is conducted. * Use the respirator continuously for at least 10 days. * Vital signs are stable: blood pressure systolic blood pressure is not lower than 70 mmHg; heartbeat is not lower than 50/min and not higher than 160/min; respiratory rate is not higher than 50/min. * When using respirator support, the oxygen concentration should not exceed 60%. Exclusion Criteria: ．At least one of the following conditions occurs: 1. Pregnancy. 2. The patient refuses to undergo weaning from the respirator training. 3. The patient has no ability to drive spontaneous breathing.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07002710 clinical trial?
This trial is open to participants of all sexes, aged 20 Years or older, studying PICS. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07002710 currently recruiting?
Yes, NCT07002710 is actively recruiting participants. Contact the research team at jsjerng@ntu.edu.tw for enrollment information.
Where is the NCT07002710 trial being conducted?
This trial is being conducted at Taipei, Taiwan.
Who is sponsoring the NCT07002710 clinical trial?
NCT07002710 is sponsored by National Taiwan University Hospital. The trial plans to enroll 40 participants.