Impact of NOL Index Intraoperative Guided Remifentanil Analgesia
Trial Parameters
Brief Summary
The Physiological Monitoring Device (PMD-200™) system is comprised of a monitor and a designated finger probe containing 4 sensors. The sensors included are Photoplethysmography (PPG), Galvanic Skin Response (GSR), Accelerometer for movement (ACC) and Thermistor for peripheral temperature (TMP). The PMD-200 is intended to be used for assessing the nociception level in anesthetized patients. The purpose of the study is confirmation of a reduction in the dosage of remifentanil allowed by the monitoring of nociception by the NOL which could open the way to a double control of the administration of anesthetic agents: control of the administration of hypnotics by the bispectral index (BIS) and control of the administration of opiate by the NOL.
Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years old * American Society of Anesthesiologists score (ASA) I, II or III stable * Laparotomy or laparoscopy for major, planned, digestive, urological or gynecological surgery under total intravenous anesthesia (expected total duration \> 90 minutes) * Having sign an informed consent form prior to any study specific procedure * Being covered by a national health insurance Non-Inclusion Criteria: * Pregnancy/lactation * Patient with antiarrhythmic agents * Patient with Central nervous system disorder * Patient with veinous approach difficulties * Patient at risk of difficult mask ventilation or difficult intubation * Concomitant use of any type of anesthesia other than general anesthesia (epidural anesthesia, spinal anesthesia, wall block, pericatricial infiltration). Wall blocks and pericatricial infiltrations are allowed if they are carried out at the end of the intervention * Allergy or intolerance to any of the study drugs * Patient not understanding