NCT07570771 IMPACT OF DIALYSIS DURATION AND DIURESIS ON BLADDER CAPACITY AND COMPLIANCE IN END STAGE RENAL DISEASE PATIENTS AWAITING RENAL TRANSPLANT
| NCT ID | NCT07570771 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Sindh Institute of Urology and Transplantation |
| Condition | End-Stage Renal Disease Requiring Haemodialysis |
| Study Type | OBSERVATIONAL |
| Enrollment | 87 participants |
| Start Date | 2026-02-02 |
| Primary Completion | 2027-02 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 87 participants in total. It began in 2026-02-02 with a primary completion date of 2027-02.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Patients with end-stage renal disease (ESRD) who are on dialysis for a long time may experience bladder problems as their urine output decreases and normal bladder filling is lacking. As a result, bladder capacity may be reduced and compliance may deteriorate, which can impact the success of kidney transplantation. Our prospective observational study is designed to investigate how dialysis duration and residual urine output (diuresis) influence bladder capacity and compliance in ESRD patients who are waiting for kidney transplantation. The adult patients undergoing regular dialysis will be assessed clinically, and they will also be subjected to laboratory tests, imaging, and urodynamic studies. Through this study, we aim to determine the frequency of bladder malfunction and its correlation with the length of dialysis and the amount of urine excretion. The results might enhance the pre-transplant workup and offer a basis for urological post-transplantation management that could minimize complications.
Eligibility Criteria
Inclusion Criteria: * Patients aged 18-65 years diagnosed with end-stage renal disease (ESRD) * Patients on maintenance dialysis for a duration of 6 to 24 months * ESRD secondary to non-urological causes * Patients awaiting renal transplantation Exclusion Criteria: * Patients with diabetes mellitus * Patients with neurogenic bladder * Patients with prior urological surgeries * Patients with active urinary tract infection * Patients with pre-existing lower urinary tract symptoms before dialysis * Patients on medications affecting lower urinary tract function * Patients with neurological or systemic diseases affecting bladder function
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07570771 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying End-Stage Renal Disease Requiring Haemodialysis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07570771 currently recruiting?
Yes, NCT07570771 is actively recruiting participants. Contact the research team at anum.parekh@yahoo.com for enrollment information.
Where is the NCT07570771 trial being conducted?
This trial is being conducted at Karachi, Pakistan.
Who is sponsoring the NCT07570771 clinical trial?
NCT07570771 is sponsored by Sindh Institute of Urology and Transplantation. The trial plans to enroll 87 participants.