← Back to Clinical Trials
Recruiting Phase 4 NCT06509503
Impact of Combined Oral Contraceptive Pills on Migraine
Trial Parameters
Condition Migraine
Sponsor Kafrelsheikh University
Study Type INTERVENTIONAL
Phase Phase 4
Enrollment 400
Sex FEMALE
Min Age 18 Years
Max Age 55 Years
Start Date 2024-07-15
Completion 2025-05-15
Interventions
Combined oral contraceptiveVaginal Ring
Brief Summary
The investigators will assess the effect of combined oral contraceptive pills (COCs) on migraine features and treatment response to allow better interpretation of the exact consequence of hormonal contraceptive use on migraineurs.
Eligibility Criteria
Inclusion Criteria: * female migraine patients on COCs or mechanical contraceptive methods, according to the International Classification of Headache Disorders 3rd edition, aged 18-55 years Exclusion Criteria: 1. Patients with major neurological conditions such as (epilepsy, ischemic or hemorrhagic stroke, multiple sclerosis, mitochondrial diseases, and brain tumors). 2. pregnant, lactating, and menopausal patients. 3. Patients with any contraindications to ibuprofen or propranolol.