NCT04993859 Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children
| NCT ID | NCT04993859 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Colorado, Denver |
| Condition | Survivors of Childhood Cancer |
| Study Type | OBSERVATIONAL |
| Enrollment | 152 participants |
| Start Date | 2021-06-02 |
| Primary Completion | 2026-07-09 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 152 participants in total. It began in 2021-06-02 with a primary completion date of 2026-07-09.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.
Eligibility Criteria
Inclusion Criteria: * Children aged 5-13 years old * A history of cancer * Treatment with a chemotherapy regimen including VCR and/or DOX * Completion of chemotherapy at least one year prior to study enrollment and survey completion. Exclusion Criteria: * Patients with a: * Primary pelvic tumor * Pelvic irradiation * Pre-existing bladder/bowel dysfunction * Spinal defects * Neurologic disorder * Neuro-oncologic tumor or brain metastasis * Cyclophosphamide or ifosfamide therapy
Contact & Investigator
Nicholas Cost, MD
PRINCIPAL INVESTIGATOR
Children's Hospital Colorado
Frequently Asked Questions
Who can join the NCT04993859 clinical trial?
This trial is open to participants of all sexes, aged 5 Years or older, up to 13 Years, studying Survivors of Childhood Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04993859 currently recruiting?
Yes, NCT04993859 is actively recruiting participants. Contact the research team at gemma.beltran@childrenscolorado.org for enrollment information.
Where is the NCT04993859 trial being conducted?
This trial is being conducted at Aurora, United States.
Who is sponsoring the NCT04993859 clinical trial?
NCT04993859 is sponsored by University of Colorado, Denver. The principal investigator is Nicholas Cost, MD at Children's Hospital Colorado. The trial plans to enroll 152 participants.
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