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Recruiting NCT06777628

NCT06777628 Immunophenotype of PBMC to Early Predict Response to Immunotherapy in Hepatocellular Carcinoma

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Clinical Trial Summary
NCT ID NCT06777628
Status Recruiting
Phase
Sponsor IRCCS Azienda Ospedaliero-Universitaria di Bologna
Condition Liver Cancer, Adult
Study Type OBSERVATIONAL
Enrollment 100 participants
Start Date 2024-09-15
Primary Completion 2026-10-15

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Immunochemotherapy combined with antiangiogenic

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 100 participants in total. It began in 2024-09-15 with a primary completion date of 2026-10-15.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The study is aimed to test the performance of a simple, easy, reproducible cytofluorimetric assay to complement imaging studies for: * predicting response to immune-therapeutic regimens in HCC in the early phase of treatment, * to rule out pseudo-progression, * to early predict the escape from effectiveness of treatment.

Eligibility Criteria

Inclusion Criteria: * age ≥ 18 years * diagnosis of HCC * execution of laboratory tests and subsequent treatments and follow-up at our center. * obtained written informed consent to the study participation Exclusion Criteria: * immune-related concomitant diseases * HIV infection

Contact & Investigator

Central Contact

Laura Gramantieri, MD

✉ laura.gramantieri@aosp.bo.it

📞 0512142579

Principal Investigator

Laura Gramantieri

PRINCIPAL INVESTIGATOR

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Frequently Asked Questions

Who can join the NCT06777628 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Liver Cancer, Adult. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06777628 currently recruiting?

Yes, NCT06777628 is actively recruiting participants. Contact the research team at laura.gramantieri@aosp.bo.it for enrollment information.

Where is the NCT06777628 trial being conducted?

This trial is being conducted at Bologna, Italy.

Who is sponsoring the NCT06777628 clinical trial?

NCT06777628 is sponsored by IRCCS Azienda Ospedaliero-Universitaria di Bologna. The principal investigator is Laura Gramantieri at IRCCS Azienda Ospedaliero-Universitaria di Bologna. The trial plans to enroll 100 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology