| NCT ID | NCT07362511 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Amsterdam |
| Condition | Major Depressive Diorder |
| Study Type | INTERVENTIONAL |
| Enrollment | 12 participants |
| Start Date | 2025-12-01 |
| Primary Completion | 2026-08-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 12 participants in total. It began in 2025-12-01 with a primary completion date of 2026-08-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
In the current study we aim to investigate the feasibility, acceptability, and effectiveness of ImRs offered by mental health assistants within primary care to reduce depressive symptoms. In a single-case experimental design (SCED) study, the following hypotheses will be tested: 1. ImRs results in a reduction of depressive symptoms compared to baseline, and this reduction lasts up to six months. 2. Patients with complaints of depressive symptoms find ImRs an acceptable form of intervention when offered by mental health assistants within a general practice setting. Participants will wait for 2-4 weeks and then receive 5 sessions of ImRs over a period of 10 weeks. During these sessions, negative memories related to their depressed feelings are rescripted.
Eligibility Criteria
Inclusion Criteria: * Main complaint of depressive feelings, as indicated by both the mental health assistant and the patient. * HADS score for the depression subscale ≥ 11. * Ability to understand, read, write and speak Dutch or English. * Age between 18 and 70. * Willingness to participate in the study and treatment. Exclusion Criteria: * Acute suicide risk (BDI-II-item9 score of 3). * If the mental health assistant suspects that the patient may have a primary diagnosis of bipolar disorder, psychosis, substance use disorder, low IQ, or if the patient suffers from serious neurological problems such as dementia, then the patient is not included. There will not be a formal assessment of a primary diagnosis.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07362511 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Major Depressive Diorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07362511 currently recruiting?
Yes, NCT07362511 is actively recruiting participants. Contact the research team at l.e.stemerding@uva.nl for enrollment information.
Where is the NCT07362511 trial being conducted?
This trial is being conducted at Amsterdam, Netherlands.
Who is sponsoring the NCT07362511 clinical trial?
NCT07362511 is sponsored by University of Amsterdam. The trial plans to enroll 12 participants.