IgA Nephropathy Registration Initiative of High Quality (INSIGHT)
Trial Parameters
Brief Summary
The investigators are registering all biopsy-proven primary IgA nephropathy (IgAN) patients at recruited hospitals and developing a IgAN database in China. Patients will be follow-up every one year, and both baseline and follow-up information will be entered into the registration system. All-cause and cardiovascular mortality and a composite renal outcome of doubling of serum creatinine and end stage renal failure (ESRD, defined as initiation of dialysis or kidney transplantation) of IgAN patients will be compared using the IgAN database.
Eligibility Criteria
Inclusion Criteria: 1. Biopsy-proven primary IgAN patients; 2. age ≥14 years old 3. Adequate biopsy sample containing ≥8 glomeruli. Exclusion Criteria: Secondary causes of mesangial IgA deposition, such as Henoch-Schonlein purpura nephritis, systemic lupus erythematosus, liver cirrhosis and et al; eGFR≤15ml/min/1.73m2 at biopsy.