NCT06966336 IEEM- Work:Rest Cycles in Burn Survivors- Humidity
| NCT ID | NCT06966336 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Texas Southwestern Medical Center |
| Condition | Hyperthermia |
| Study Type | OBSERVATIONAL |
| Enrollment | 70 participants |
| Start Date | 2025-08-15 |
| Primary Completion | 2030-08-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 70 participants in total. It began in 2025-08-15 with a primary completion date of 2030-08-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this project is to identify the effects of a severe burn injuries in humans on core temperature responses during work:rest cycles while in a heated environment.
Eligibility Criteria
Inclusion Criteria for Non-burned Individuals: * Participants must be free of any significant underlying medical problems based upon a detailed medical history and physical exam, and normal resting electrocardiogram. Participants must be between the ages of 18 and 65. Exclusion Criteria for Non-burned Individuals: * Known heart disease; other chronic medical conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, and uncontrolled hypertension, lung disease, etc.; as well as serious abnormalities detected on routine screening. Current smokers, as well as individuals who regularly smoked within the past 3 years will be excluded. Participants may also be excluded if body mass index is ≥ 31 kg/m2 will likewise be excluded. Participants must not have had a serious burn injury requiring more than 1 night stay in the hospital. Inclusion Criteria for Individuals with up to 40% of their body surface area burned (moderate burn group): \- Participants must be free of any significant underlying medical problems based upon a detailed medical history and physical exam, and normal resting electrocardiogram. Participants who have sustained a burn injury must have a burn covering 20-40% of their body surface area and 50% of those burns must be full-thickness burns requiring skin grafts. Participants must be between the ages of 18 and 65. Exclusion Criteria for Individuals with up to 40% of their body surface area burned (moderate burn group): \- Known heart disease; other chronic medical conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, and uncontrolled hypertension, lung disease, etc.; as well as serious abnormalities detected on routine screening. Current smokers, as well as individuals who regularly smoked within the past 3 years will be excluded. Participants may also be excluded if body mass index is ≥ 31 kg/m2 will likewise be excluded. Inclusion Criteria for Individuals with greater than 40% of their body surface area burned (large burn group): \- Participants must be free of any significant underlying medical problems based upon a detailed medical history and physical exam, and normal resting electrocardiogram. Participants who have sustained a burn injury must have a burn covering more than 40% of their body surface area and 50% of those burns must be full-thickness burns requiring skin grafts. Participants must be between the ages of 18 and 65. Exclusion Criteria for Individuals with greater than 40% of their body surface area burned (large burn group): \- Known heart disease; other chronic medical conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, and uncontrolled hypertension, lung disease, etc.; as well as serious abnormalities detected on routine screening. Current smokers, as well as individuals who regularly smoked within the past 3 years will be excluded. Participants may also be excluded if body mass index is ≥ 31 kg/m2 will likewise be excluded.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06966336 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Hyperthermia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06966336 currently recruiting?
Yes, NCT06966336 is actively recruiting participants. Contact the research team at craigcrandall@texashealth.org for enrollment information.
Where is the NCT06966336 trial being conducted?
This trial is being conducted at Dallas, United States.
Who is sponsoring the NCT06966336 clinical trial?
NCT06966336 is sponsored by University of Texas Southwestern Medical Center. The trial plans to enroll 70 participants.