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Recruiting NCT07153458

NCT07153458 Identification of New Non-invasive, Predictive, and Diagnostic Biomarkers for Colorectal Cancer

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Clinical Trial Summary
NCT ID NCT07153458
Status Recruiting
Phase
Sponsor Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Condition CRC (Colorectal Cancer)
Study Type OBSERVATIONAL
Enrollment 60 participants
Start Date 2025-12-01
Primary Completion 2026-12-01

Trial Parameters

Condition CRC (Colorectal Cancer)
Sponsor Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Study Type OBSERVATIONAL
Phase N/A
Enrollment 60
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2025-12-01
Completion 2026-12-01

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Brief Summary

The study in question is an observational study that aims to identify new non-invasive biomarkers present in the serum of patients with CRC and, subsequently, to create a score capable of predicting the development of CRC. It is an observational study with 3 enrollment arms: Arm 1: Patients undergoing surgery at the U.O.C. of Surgery, with a CRC diagnosis; Arm 2: Subjects with a negative result from the endoscopic examination; Arm 3: Subjects in whom the presence of an adenoma with high-grade dysplasia is found, a condition considered pre-cancerous.

Eligibility Criteria

Inclusion Criteria: * AIM 1: Patients undergoing surgery at the U.O.C. of Surgery, with a diagnosis of CRC. * AIM 2: Subjects without colon disease. * AIM 3: Subjects with adenoma and high-grade dysplasia. Exclusion Criteria: * Subject with any other pathology not included in the inclusion criteria.

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